User profiles for Glen Wheeler

Glen Wheeler

Senior Research Fellow, Marine Biological Association
Verified email at mba.ac.uk
Cited by 10075

The biosynthetic pathway of vitamin C in higher plants

GL Wheeler, MA Jones, N Smirnoff - Nature, 1998 - nature.com
Vitamin C (L-ascorbic acid) has important antioxidant and metabolic functions in both plants
and animals, but humans, and a few other animal species, have lost the capacity to …

Ascorbic acid in plants: biosynthesis and function

N Smirnoff, GL Wheeler - Critical reviews in plant sciences, 2000 - Taylor & Francis
Ascorbic acid (vitamin C) is an abundant component of plants. It reaches a concentration of
over 20 mM in chloroplasts and occurs in all cell compartments, including the cell wall. It has …

[HTML][HTML] The Marine Microbial Eukaryote Transcriptome Sequencing Project (MMETSP): illuminating the functional diversity of eukaryotic life in the oceans through …

…, PE Umale, D Vaulot, B Wawrik, GL Wheeler… - PLoS …, 2014 - journals.plos.org
Current sampling of genomic sequence data from eukaryotes is relatively poor, biased, and
inadequate to address important questions about their biology, evolution, and ecology; this …

Genetic evidence for the role of GDP-mannose in plant ascorbic acid (vitamin C) biosynthesis

PL Conklin, SR Norris, GL Wheeler… - Proceedings of the …, 1999 - National Acad Sciences
Vitamin C (l-ascorbic acid; AsA) acts as a potent antioxidant and cellular reductant in plants
and animals. AsA has long been known to have many critical physiological roles in plants, …

[HTML][HTML] Pan genome of the phytoplankton Emiliania underpins its global distribution

…, P Von Dassow, K Valentin, Y Van de Peer, G Wheeler… - Nature, 2013 - nature.com
Coccolithophores have influenced the global climate for over 200 million years 1 . These
marine phytoplankton can account for 20 per cent of total carbon fixation in some systems 2 . …

Antisense suppression of l‐galactose dehydrogenase in Arabidopsis thaliana provides evidence for its role in ascorbate synthesis and reveals light modulated l …

S Gatzek, GL Wheeler, N Smirnoff - The Plant Journal, 2002 - Wiley Online Library
l‐Galactose dehydrogenase (l‐GalDH), a novel enzyme that oxidizes l‐Gal to l‐galactono‐1,4‐lactone
(l‐GalL), has been purified from pea seedlings and cloned from Arabidopsis …

Insights into the Evolution of Vitamin B12 Auxotrophy from Sequenced Algal Genomes

KE Helliwell, GL Wheeler, KC Leptos… - Molecular biology …, 2011 - academic.oup.com
Vitamin B 12 (cobalamin) is a dietary requirement for humans because it is an essential
cofactor for two enzymes, methylmalonyl-CoA mutase and methionine synthase (METH). Land …

[HTML][HTML] A Voltage-Gated H+ Channel Underlying pH Homeostasis in Calcifying Coccolithophores

AR Taylor, A Chrachri, G Wheeler, H Goddard… - PLoS …, 2011 - journals.plos.org
Marine coccolithophorid phytoplankton are major producers of biogenic calcite, playing a
significant role in the global carbon cycle. Predicting the impacts of ocean acidification on …

Insights into the red algae and eukaryotic evolution from the genome of Porphyra umbilicalis (Bangiophyceae, Rhodophyta)

…, E Ficko-Blean, GL Wheeler… - Proceedings of the …, 2017 - National Acad Sciences
Porphyra umbilicalis (laver) belongs to an ancient group of red algae (Bangiophyceae), is
harvested for human food, and thrives in the harsh conditions of the upper intertidal zone. …

Ca2+ signalling in plants and green algae–changing channels

GL Wheeler, C Brownlee - Trends in plant science, 2008 - cell.com
Eukaryotic cells generate cytosolic Ca 2+ signals via Ca 2+ -conducting channels in cellular
membranes. Plants and animals exhibit substantial differences in their complement of Ca 2+ …