Immunotherapy holds great promise for the treatment of pediatric cancers. In neuroblastoma,
the recent implementation of anti-GD2 antibody Dinutuximab into the standard of care has …

BACKGROUND The current study was conducted to expedite international standardized
reporting of bone marrow disease in children with neuroblastoma and to improve equivalence …

Background Neuroblastoma is an embryonic tumour of childhood that originates in the
neural crest. It is the second most common extracranial malignant solid tumour of childhood.

Whole-genome sequencing detected structural rearrangements of TERT in 17 of 75 high-stage
neuroblastomas, with five cases resulting from chromothripsis. Rearrangements were …

Kidney tumours are among the most common solid tumours in children, comprising distinct
subtypes differing in many aspects, including cell-of-origin, genetics, and pathology. Pre-…

Purpose Wilms tumor (WT) is the most common pediatric renal tumor. Treatment planning
under International Society of Paediatric Oncology (SIOP) protocols is based on staging and …

Purpose Polymerase chain reaction (PCR)–based detection of minimal residual disease (MRD)
in neuroblastoma can be used to monitor therapy response and to evaluate stem cell …

Introduction Neuroblastoma (NBL) accounts for 10% of the paediatric malignancies and is
responsible for 15% of the paediatric cancer-related deaths. Vanillylmandelic acid (VMA) and …

Background: PCR-based detection of minimal residual disease (MRD) in neuroblastoma (NB)
patients can be used for initial staging and monitoring therapy response in bone marrow (…

Neuroblastoma is the most common extracranial solid malignancy in children. At diagnosis,
approximately 50% of patients present with metastatic disease. These patients are at high …