Context Although bipolar disorder may have its onset during childhood, little is known about
national trends in the diagnosis and management of bipolar disorder in young people. …

Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …

Context Although there are indications that antipsychotic drugs are increasingly used to treat
children and adolescents, little is known about the characteristics of those who receive them…

The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a
collaborative network of researchers working together on a range of large-scale studies that …

Depressive disorders account for a large and increasing global burden of disease. Although
the condition of many patients improves with medication, only a minority experience full …

Importance Despite evidence of the increasing use of psychotropic medications, little is known
about the broader changes in the delivery of outpatient mental health treatment to children…

Background Lithium is a first-line treatment in bipolar disorder, but individual response is
variable. Previous studies have suggested that lithium response is a heritable trait. However, …

BACKGROUND: In a recent study of several antidepressant drugs in hospitalized, non-Hispanic
White patients, Binder et al. reported association of markers located within the FKBP5 …

BACKGROUND: Ketamine has rapid antidepressant effects lasting as long as 1 week in
patients with major depressive disorder (MDD) and bipolar depression (BD). Ketamine is …

Context TheHTTLPR, a functional polymorphism of the serotonin transporter gene solute
carrier family 6 (neurotransmitter transporter, serotonin), member 4 (SLC6A4), promoter, affects …