Whether nucleic acids that circulate in blood have any patho-physiological functions in the
host have not been explored. We report here that far from being inert molecules, circulating …

We examined the possible molecular mechanisms underlying the cytotoxicity and anticarcinogenic
potential of Mentha leaf extracts (petroleum ether, benzene, chloroform, ethyl acetate, …

Bystander cells of the tumor microenvironment show evidence of DNA damage and inflammation
that can lead to their oncogenic transformation. Mediator (s) of cell–cell communication …

Radiation-induced bystander effect (RIBE) is a poorly understood phenomenon wherein non-targeted
cells exhibit effects of radiation. We have reported that cell-free chromatin (cfCh) …

Lymphocyte homeostasis in type 2 diabetes mellitus (T2DM) is associated with increased
susceptibility to infections. Mitochondrial oxidative stress is implicated primarily in the immune …

Intervention to decelerate, arrest, or reverse the process of carcinogenesis by the use of either
natural or synthetic agents individually or in combination has emerged as a promising and …

Billions of cells die in the body every day, and cell-free chromatin particles (cfChPs) which
are released from them enter into the extracellular compartments of the body, including into …

Frontiers | A pro-oxidant combination of resveratrol and copper down-regulates hallmarks of
cancer and immune checkpoints in patients with advanced oral cancer: Results of an …

The role of oxidative stress is often attributed in environmental renal diseases. Isocyanates,
a ubiquitous chemical group with diverse industrial applications, are known to undergo bio-…

Stress induced premature senescence (SIPS) is a relative extension to the concept of
exogenous cellular insult. Besides persistent double strand (ds) DNA breaks and increased β-…