User profiles for Govardhan Anande
 | Dr. Govardhan AnandePost Doctoral Researcher Verified email at unsw.edu.au Cited by 279 |
The RNA Atlas expands the catalog of human non-coding RNAs
Existing compendia of non-coding RNA (ncRNA) are incomplete, in part because they are
derived almost exclusively from small and polyadenylated RNAs. Here we present a more …
derived almost exclusively from small and polyadenylated RNAs. Here we present a more …
[HTML][HTML] Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers
Human endogenous retroviruses (HERV) form a substantial part of the human genome, but
mostly remain transcriptionally silent under strict epigenetic regulation, yet can potentially be …
mostly remain transcriptionally silent under strict epigenetic regulation, yet can potentially be …
Srsf2 P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells
Mutations in SRSF2 occur in myelodysplastic syndromes (MDS) and MDS/myeloproliferative
neoplasms (MPN). SRSF2 mutations cluster at proline 95, with the most frequent mutation …
neoplasms (MPN). SRSF2 mutations cluster at proline 95, with the most frequent mutation …
RNA splicing alterations induce a cellular stress response associated with poor prognosis in acute myeloid leukemia
Purpose: RNA splicing is a fundamental biological process that generates protein diversity
from a finite set of genes. Recurrent somatic mutations of splicing factor genes are common in …
from a finite set of genes. Recurrent somatic mutations of splicing factor genes are common in …
Constitutive CHK1 expression drives a pSTAT3–CIP2A circuit that promotes glioblastoma cell survival and growth
High expression of CIP2A in gliomas is maintained by a CHK1-dependent pSTAT3–CIP2A
recursive loop; interrupting CIP2A induces cell senescence and slows GBM growth adding …
recursive loop; interrupting CIP2A induces cell senescence and slows GBM growth adding …
[HTML][HTML] The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors
Chemo-resistance in acute myeloid leukemia (AML) patients is driven by leukemic stem
cells (LSCs) resulting in high rates of relapse and low overall survival. Here, we demonstrate …
cells (LSCs) resulting in high rates of relapse and low overall survival. Here, we demonstrate …
The RNA Atlas, a single nucleotide resolution map of the human transcriptome
The human transcriptome consists of various RNA biotypes including multiple types of non-coding
RNAs (ncRNAs). Current ncRNA compendia remain incomplete partially because …
RNAs (ncRNAs). Current ncRNA compendia remain incomplete partially because …
The RNA Atlas expands the catalog of human non-coding RNAs (June, 10.1038/s41587-021-00936-1, 2021)
In the version of this Article initially published, there was an error in Fig. 3. Specifically, in Fig.
3a, the lower blue equation at left, the denominator in the final term was a duplication of the …
3a, the lower blue equation at left, the denominator in the final term was a duplication of the …
RBM17 Mediates Evasion of Pro-Leukemic Factors from Splicing-coupled NMD to Enforce Leukemic Stem Cell Maintenance
L Liu, A Vujovic, N Deshpande, S Sathe, G Anande… - 2021 - researchsquare.com
Chemo-resistance in acute myeloid leukemia (AML) patients is driven by leukemic stem cells
(LSC) resulting in high rates of relapse and low overall survival. Here, we demonstrate that …
(LSC) resulting in high rates of relapse and low overall survival. Here, we demonstrate that …
RNA splicing alterations induce a cellular stress response associated with poor prognosis in AML
RNA splicing is a fundamental biological process that generates protein diversity from a finite
set of genes. Recurrent somatic mutations of splicing factor genes are relatively uncommon …
set of genes. Recurrent somatic mutations of splicing factor genes are relatively uncommon …