User profiles for Govinda Kamath

Govinda M. Kamath

10x Genomics
Verified email at alumni.stanford.edu
Cited by 1863

Random access in large-scale DNA data storage

…, S Yekhanin, K Makarychev, MZ Racz, G Kamath… - Nature …, 2018 - nature.com
Synthetic DNA is durable and can encode digital data with high density, making it an attractive
medium for data storage. However, recovering stored data on a large-scale currently …

Optimal linear codes with a local-error-correction property

N Prakash, GM Kamath, V Lalitha… - 2012 IEEE International …, 2012 - ieeexplore.ieee.org
Motivated by applications to distributed storage, Gopalan et al recently introduced the
interesting notion of information-symbol locality in a linear code. By this it is meant that each …

Codes with local regeneration and erasure correction

GM Kamath, N Prakash, V Lalitha… - IEEE Transactions on …, 2014 - ieeexplore.ieee.org
Regenerating codes and codes with locality are two coding schemes that have recently been
proposed, which in addition to ensuring data collection and reliability, also enable efficient …

[HTML][HTML] Fast and accurate single-cell RNA-seq analysis by clustering of transcript-compatibility counts

V Ntranos, GM Kamath, JM Zhang, L Pachter, DN Tse - Genome biology, 2016 - Springer
Current approaches to single-cell transcriptomic analysis are computationally intensive and
require assay-specific modeling, which limits their scope and generality. We propose a …

HINGE: long-read assembly achieves optimal repeat resolution

GM Kamath, I Shomorony, F Xia, TA Courtade… - Genome …, 2017 - genome.cshlp.org
Long-read sequencing technologies have the potential to produce gold-standard de novo
genome assemblies, but fully exploiting error-prone reads to resolve repeats remains a …

Genome-scale screens identify factors regulating tumor cell responses to natural killer cells

…, JG Bryan, C Zhu, L Wang, I Tariq, GM Kamath… - Nature Genetics, 2021 - nature.com
To systematically define molecular features in human tumor cells that determine their
degree of sensitivity to human allogeneic natural killer (NK) cells, we quantified the NK cell …

[PDF][PDF] Valid post-clustering differential analysis for single-cell RNA-Seq

JM Zhang, GM Kamath, NT David - Cell systems, 2019 - cell.com
Single-cell computational pipelines involve two critical steps: organizing cells (clustering)
and identifying the markers driving this organization (differential expression analysis). State-of-…

Scaling up DNA data storage and random access retrieval

…, S Yekhanin, K Makarychev, MZ Racz, G Kamath… - BioRxiv, 2017 - biorxiv.org
Current storage technologies can no longer keep pace with exponentially growing amounts
of data. Synthetic DNA offers an attractive alternative due to its potential information density …

Community recovery in graphs with locality

Y Chen, G Kamath, C Suh… - … conference on machine …, 2016 - proceedings.mlr.press
Motivated by applications in domains such as social networks and computational biology,
we study the problem of community recovery in graphs with locality. In this problem, pairwise …

Knowledge distillation as semiparametric inference

T Dao, GM Kamath, V Syrgkanis, L Mackey - arXiv preprint arXiv …, 2021 - arxiv.org
A popular approach to model compression is to train an inexpensive student model to mimic
the class probabilities of a highly accurate but cumbersome teacher model. Surprisingly, …