Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …

Understanding the diversity of cell types in the brain has been an enduring challenge and
requires detailed characterization of individual neurons in multiple dimensions. To …

The neocortex is disproportionately expanded in human compared with mouse 1 , 2 , both
in its total volume relative to subcortical structures and in the proportion occupied by …

We present a unique, extensive, and open synaptic physiology analysis platform and dataset.
Through its application, we reveal principles that relate cell type to synaptic properties and …

Jackson et al.(2020) have recently described the extraordinary times we face as a result of
the COVID-19 pandemic. As we write, the number of cases and the associated mortality …

To understand the brain we must relate neurons’ functional responses to the circuit architecture
that shapes them. Here, we present a large functional connectomics dataset with dense …

Human cortex transcriptomic studies have revealed a hierarchical organization of γ-aminobutyric
acid–producing (GABAergic) neurons from subclasses to a high diversity of more …

Companion animal ownership has been associated with a wide variety of physical and
psychological health benefits. The extent to which a person gains any welfare advantages from …

The mitotic spindle checkpoint protein Bub1 has been found to be mutated at low frequency
in certain human cancers characterized by aneuploidy. Simian virus 40 large T antigen …

The spindle assembly checkpoint is an important surveillance mechanism that ensures high
fidelity mitotic chromosome segregation. This is accomplished by monitoring whether sister …