Predicting immune responses before vaccination is challenging because of the complexity
of the governing parameters. Nevertheless, recent work has shown that B cell receptor (BCR)-…

Sequence homology between SARS-CoV-2 and common-cold human coronaviruses (HCoVs)
raises the possibility that memory responses to prior HCoV infection can affect T cell …

Seasonal “common-cold” human coronaviruses are widely spread throughout the world and
are mainly associated with mild upper respiratory tract infections. The emergence of highly …

Activation of immune cells (but not B cells) with lectins is widely known. We used the structurally
defined interaction between influenza hemagglutinin (HA) and its cell surface receptor …

Initial TCR affinity for peptide Ag is known to impact the generation of memory; however, its
contributions later, when effectors must again recognize Ag at 5–8 d postinfection to become …

Human roseolovirus U20 and U21 are type I membrane glycoproteins that have been
implicated in immune evasion by interfering with recognition of classical and non-classical MHC …

Acute kidney injury, often caused by an ischemic insult, is associated with significant short-term
morbidity and mortality, and increased risk of chronic kidney disease. The factors …

OPCML, a tumor suppressor gene, is frequently silenced epigenetically in ovarian and other
cancers. Here we report, by analysis of databases of tumor sequences, the observation of …

In the United States, congressional redistricting follows a decennial Census. Gerrymandering
can result from selection of district lines regardless of political parties. Understanding the …

The impact of initial peptide antigen affinity for TCR in driving memory fate has been studied
previously, however its contributions when effectors contract to memory is unclear. To …