The ability to measure human aging from molecular profiles has practical implications in
many fields, including disease prevention and treatment, forensics, and extension of life. …

Background The domestic pig (Sus scrofa) is important both as a food source and as a
biomedical model given its similarity in size, anatomy, physiology, metabolism, pathology, and …

The manner in which microorganisms utilize their metabolic processes can be predicted
using constraint-based analysis of genome-scale metabolic networks. Herein, we present the …

Objective This study introduces a novel method, referred to as SeqFF, for estimating the fetal
DNA fraction in the plasma of pregnant women and to infer the underlying mechanism that …

Pseudomonas aeruginosa is an antibiotic-refractory pathogen with a large genome and
extensive genotypic diversity. Historically, P. aeruginosa has been a major model system for …

BACKGROUND The development of sequencing-based noninvasive prenatal testing (NIPT)
has been largely focused on whole-chromosome aneuploidies (chromosomes 13, 18, 21, X, …

BACKGROUND: The present study evaluated the accumulated changes in hair cortisol
levels of patients with posttraumatic stress disorder (PTSD) attributed to the 2008 Wenchuan …

Genome-wide association study (GWAS) has identified genetic variants in the promoter
region of the high temperature requirement factor A1 (HTRA1) gene associated with age-related …

Robust molecular tool kits in model and industrial microalgae are key to efficient targeted
manipulation of endogenous and foreign genes in the nuclear genome for basic research and, …

Traditional antibody optimization approaches involve screening a small subset of the
available sequence space, often resulting in drug candidates with suboptimal binding affinity, …