Previous studies provided evidence that sepsis-induced muscle proteolysis in experimental
animals is caused by increased ubiquitin-proteasome-dependent protein breakdown. It is …

Imaging is crucial in the assessment of children with a primary hepatic malignancy. Since its
inception in 1992, the PRETEXT (PRE-Treatment EXTent of tumor) system has become the …

The etiology and pathogenesis of bile duct obstruction in children with biliary atresia are largely
unknown. We have previously reported that, despite phenotypic heterogeneity, genomic …

Background Biliary atresia is the commonest cause of pathological jaundice in infants and
the leading indication for liver transplantation in children worldwide. The cause and …

We tested the role of different intracellular proteolytic pathways in sepsis-induced muscle
proteolysis. Sepsis was induced in rats by cecal ligation and puncture; controls were sham …

International collaborative efforts in hepatoblastoma have led to increased refinements in
the use of the PRETEXT and post-treatment extent to define prognosis and surgical …

Objective: The goals of this study were to describe the clinical and anatomic features of
infants undergoing Kasai portoenterostomy (KPE) for biliary atresia (BA) and to examine …

Objectives In a large cohort of children with intestinal failure (IF), we sought to determine the
cumulative incidence of achieving enteral autonomy and identify patient and institutional …

Objectives To prospectively assess the value of serum total bilirubin (TB) within 3ámonths of
hepatoportoenterostomy (HPE) in infants with biliary atresia as a biomarker predictive of …

Recent studies suggest that sepsis-induced increase in muscle proteolysis mainly reflects
energy-ubiquitin-dependent protein breakdown. We tested the hypothesis that glucocorticoids …