User profiles for Gregg W.C. Thomas

Gregg WC Thomas

Bioinformatics Scientist, Harvard University
Verified email at g.harvard.edu
Cited by 3860

Estimating gene gain and loss rates in the presence of error in genome assembly and annotation using CAFE 3

MV Han, GWC Thomas… - … biology and evolution, 2013 - academic.oup.com
Current sequencing methods produce large amounts of data, but genome assemblies
constructed from these data are often fragmented and incomplete. Incomplete and error-filled …

Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication

…, C Alkan, GWC Thomas… - Proceedings of the …, 2014 - National Acad Sciences
Little is known about the genetic changes that distinguish domestic cat populations from
their wild progenitors. Here we describe a high-quality domestic cat reference genome …

Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes

…, P Somboon, V Stegniy, CJ Struchiner, GWC Thomas… - Science, 2015 - science.org
INTRODUCTION Control of mosquito vectors has historically proven to be an effective
means of eliminating malaria. Human malaria is transmitted only by mosquitoes in the genus …

[HTML][HTML] Gibbon genome and the fast karyotype evolution of small apes

…, K Sonmez, B Hallers, E Terhune, GWC Thomas… - Nature, 2014 - nature.com
Gibbons are small arboreal apes that display an accelerated rate of evolutionary chromosomal
rearrangement and occupy a key node in the primate phylogeny between Old World …

[HTML][HTML] Convergent evolution of the genomes of marine mammals

AD Foote, Y Liu, GWC Thomas, T Vinař, J Alföldi… - Nature …, 2015 - nature.com
Marine mammals from different mammalian orders share several phenotypic traits adapted
to the aquatic environment and therefore represent a classic example of convergent evolution…

[HTML][HTML] A model species for agricultural pest genomics: the genome of the Colorado potato beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae)

…, G Smagghe, Z Szendrei, GWC Thomas… - Scientific reports, 2018 - nature.com
The Colorado potato beetle is one of the most challenging agricultural pests to manage. It
has shown a spectacular ability to adapt to a variety of solanaceaeous plants and variable …

[HTML][HTML] Gene content evolution in the arthropods

GWC Thomas, E Dohmen, DST Hughes, SC Murali… - Genome biology, 2020 - Springer
Background Arthropods comprise the largest and most diverse phylum on Earth and play
vital roles in nearly every ecosystem. Their diversity stems in part from variations on a …

The genome of the vervet (Chlorocebus aethiops sabaeus)

…, JR Kaplan, MJ Jorgensen, GWC Thomas… - Genome …, 2015 - genome.cshlp.org
We describe a genome reference of the African green monkey or vervet (Chlorocebus
aethiops). This member of the Old World monkey (OWM) superfamily is uniquely valuable for …

Genus-wide characterization of bumblebee genomes provides insights into their evolution and variation in ecological and behavioral traits

…, Y Wang, X Zhao, L Su, GWC Thomas… - Molecular biology …, 2021 - academic.oup.com
Bumblebees are a diverse group of globally important pollinators in natural ecosystems and
for agricultural food production. With both eusocial and solitary life-cycle phases, and some …

Determining the null model for detecting adaptive convergence from genomic data: a case study using echolocating mammals

GWC Thomas, MW Hahn - Molecular biology and evolution, 2015 - academic.oup.com
Convergent evolution occurs when the same trait arises independently in multiple lineages.
In most cases of phenotypic convergence such transitions are adaptive, so finding the …