User profiles for Gregor F.P. Schuhknecht
Gregor SchuhknechtDepartment of Molecular and Cellular Biology, Harvard University Verified email at fas.harvard.edu Cited by 533 |
Structure and function of a neocortical synapse
S Holler, G Köstinger, KAC Martin, GFP Schuhknecht… - Nature, 2021 - nature.com
In 1986, electron microscopy was used to reconstruct by hand the entire nervous system of
a roundworm, the nematode Caenorhabditis elegans 1 . Since this landmark study, high-…
a roundworm, the nematode Caenorhabditis elegans 1 . Since this landmark study, high-…
[PDF][PDF] Fly-FUCCI: A versatile tool for studying cell proliferation in complex tissues
…, M van Straaten, K Bender, GFP Schuhknecht… - Cell reports, 2014 - cell.com
One promising approach for in vivo studies of cell proliferation is the FUCCI system (fluorescent
ubiquitination-based cell cycle indicator). Here, we report the development of a …
ubiquitination-based cell cycle indicator). Here, we report the development of a …
An ultrastructural study of the thalamic input to layer 4 of primary motor and primary somatosensory cortex in the mouse
…, KAC Martin, GFP Schuhknecht - Journal of …, 2017 - Soc Neuroscience
The traditional classification of primary motor cortex (M1) as an agranular area has been
challenged recently when a functional layer 4 (L4) was reported in M1. L4 is the principal target …
challenged recently when a functional layer 4 (L4) was reported in M1. L4 is the principal target …
[HTML][HTML] Functional neuronal circuits emerge in the absence of developmental activity
The complex neuronal circuitry of the brain develops from limited information contained in
the genome. After the genetic code instructs the birth of neurons, the emergence of brain …
the genome. After the genetic code instructs the birth of neurons, the emergence of brain …
Nature over Nurture: Functional neuronal circuits emerge in the absence of developmental activity
During development, the complex neuronal circuitry of the brain arises from limited
information contained in the genome. After the genetic code instructs the birth of neurons, the …
information contained in the genome. After the genetic code instructs the birth of neurons, the …
[HTML][HTML] How synaptic strength, short-term plasticity, and input synchrony contribute to neuronal spike output
…, B Ehret, GFP Schuhknecht - PLoS Computational …, 2023 - journals.plos.org
Neurons integrate from thousands of synapses whose strengths span an order of magnitude.
Intriguingly, in mouse neocortex, the few ‘strong’ synapses are formed between similarly …
Intriguingly, in mouse neocortex, the few ‘strong’ synapses are formed between similarly …
Structure and function of a neocortical synapse
…, G Köstinger, KAC Martin, GFP Schuhknecht… - BioRxiv, 2019 - biorxiv.org
Thirty-four years since the small nervous system of the nematode C. elegans was manually
reconstructed in the electron microscope (EM) 1 , ‘high-throughput’ EM techniques now …
reconstructed in the electron microscope (EM) 1 , ‘high-throughput’ EM techniques now …
Structure and function of synapses in the first stages of processing in mouse neocortex
GFP Schuhknecht - 2019 - research-collection.ethz.ch
A grand challenge of systems neuroscience is to explain how the canonical microcircuit of
neocortex enables such a wealth of diverse functions, including our remarkable cognitive …
neocortex enables such a wealth of diverse functions, including our remarkable cognitive …
How synaptic strength, short-term plasticity, and temporal factors contribute to neuronal spike output
AG Guilabert, B Ehret, MO Buchholz, GFP Schuhknecht - bioRxiv, 2021 - biorxiv.org
To compute spiking responses, neurons integrate inputs from thousands of synapses whose
strengths span an order of magnitude. Intriguingly, in mouse neocortex, the small minority of …
strengths span an order of magnitude. Intriguingly, in mouse neocortex, the small minority of …
[HTML][HTML] Search strategy is regulated by somatostatin signaling and deep brain photoreceptors in zebrafish
EJ Horstick, Y Bayleyen, JL Sinclair, HA Burgess - BMC biology, 2017 - Springer
Background Animals use sensory cues to efficiently locate resources, but when sensory
information is insufficient, they may rely on internally coded search strategies. Despite the …
information is insufficient, they may rely on internally coded search strategies. Despite the …