Energetics of bacterial growth: balance of anabolic and catabolic reactions

JB Russell, GM Cook - Microbiological reviews, 1995 - Am Soc Microbiol
Biomass formation represents one of the most basic aspects of bacterial metabolism. While
there is an abundance of information concerning individual reactions that result in cell …

Genomic and metagenomic surveys of hydrogenase distribution indicate H2 is a widely utilised energy source for microbial growth and survival

…, CJ Jackson, MC Taylor, MB Stott, GM Cook… - The ISME …, 2016 - academic.oup.com
Recent physiological and ecological studies have challenged the long-held belief that microbial
metabolism of molecular hydrogen (H 2 ) is a niche process. To gain a broader insight …

Isolation and characterization of arsenate-reducing bacteria from arsenic-contaminated sites in New Zealand

CR Anderson, GM Cook - Current microbiology, 2004 - Springer
Two environmental sites in New Zealand were sampled (eg, water and sediment) for bacterial
isolates that could use either arsenite as an electron donor or arsenate as an electron …

Redundancy of aerobic respiratory chains in bacteria? Routes, reasons and regulation

RK Poole, GM Cook - 2000 - Elsevier
Bacteria are the most remarkable organisms in the biosphere, surviving and growing in
environments that support no other life forms. Underlying this ability is a flexible metabolism …

Physiology of mycobacteria

GM Cook, M Berney, S Gebhard, M Heinemann… - Advances in microbial …, 2009 - Elsevier
Mycobacterium tuberculosis is a prototrophic, metabolically flexible bacterium that has
achieved a spread in the human population that is unmatched by any other bacterial pathogen. …

[HTML][HTML] Unique flexibility in energy metabolism allows mycobacteria to combat starvation and hypoxia

M Berney, GM Cook - PloS one, 2010 - journals.plos.org
Mycobacteria are a group of obligate aerobes that require oxygen for growth, but paradoxically
have the ability to survive and metabolize under hypoxia. The mechanisms responsible …

Bactericidal mode of action of bedaquiline

…, D Bald, A Koul, K Andries, GM Cook - Journal of …, 2015 - academic.oup.com
Objectives It is not fully understood why inhibiting ATP synthesis in Mycobacterium species
leads to death in non-replicating cells. We investigated the bactericidal mode of action of the …

Unique rotary ATP synthase and its biological diversity

C von Ballmoos, GM Cook, P Dimroth - Annu. Rev. Biophys., 2008 - annualreviews.org
F 1 F 0 ATP synthases convert energy stored in an electrochemical gradient of H + or Na +
across the membrane into mechanical rotation, which is subsequently converted into the …

Energetics of respiration and oxidative phosphorylation in mycobacteria

GM Cook, K Hards, C Vilchèze… - Molecular Genetics …, 2014 - Wiley Online Library
The genus Mycobacterium comprises a group of obligately aerobic bacteria that have
adapted to inhabit a wide range of intracellular and extracellular environments. A fundamental …

Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection

…, S Alonso, GM Cook, M Berney… - Proceedings of the …, 2017 - National Acad Sciences
The recent discovery of small molecules targeting the cytochrome bc 1 :aa 3 in Mycobacterium
tuberculosis triggered interest in the terminal respiratory oxidases for antituberculosis …