Metabolism is one of the strongest drivers of interkingdom interactions—including those
between microorganisms and their multicellular hosts. Traditionally thought to fuel energy …

Pathogen virulence exists on a continuum. The strategies that drive symptomatic or asymptomatic
infections remain largely unknown. We took advantage of the concept of lethal dose …

Obstacles to bacterial survival and replication in the cytosol of host cells, and the mechanisms
used by bacterial pathogens to adapt to this niche are not well understood. Listeria …

Previous studies have demonstrated that Pseudomonas putida strains are not only capable
of growth on a wide range of organic substrates, but also chemotactic towards many of these …

Listeria monocytogenes , the causative agent of listeriosis, is an intracellular pathogen that
is exquisitely evolved to survive and replicate in the cytosol of eukaryotic cells. Eukaryotic …

The success of Staphylococcus aureus as a pathogen is due to its capability of fine‐tuning
its cellular physiology to meet the challenges presented by diverse environments, which …

Light organs (LO) with symbiotic bioluminescent bacteria are hallmarks of many bobtail
squid species. These organs possess structural and functional features to modulate light, …

Through unknown mechanisms, the host cytosol restricts bacterial colonization; therefore,
only professional cytosolic pathogens are adapted to colonize this host environment. Listeria …

Listeria monocytogenes is a Gram-positive, intracellular pathogen that is highly adapted to
invade and replicate in the cytosol of eukaryotic cells. Intermediate metabolites in the …

Infections induce dramatic rearrangements in host macro-and micronutrient processes [1]
and likely reflect host adaptive mechanisms to defend against infection. Traditional models to …