[HTML][HTML] A tug of war: pseudorabies virus and host antiviral innate immunity

G Ye, H Liu, Q Zhou, X Liu, L Huang, C Weng - Viruses, 2022 - mdpi.com
The non-specific innate immunity can initiate host antiviral innate immune responses within
minutes to hours after the invasion of pathogenic microorganisms. Therefore, the natural …

African swine fever virus H240R protein inhibits the production of type I interferon through disrupting the oligomerization of STING

G Ye, H Liu, X Liu, W Chen, J Li, D Zhao… - Journal of …, 2023 - Am Soc Microbiol
… Weng, and Guangqiang Ye conceived and coordinated the study. Guangqiang Ye and Li …
Guangqiang Ye and Hongyang Liu contributed equally to this work. Author order was …

African swine fever virus HLJ/18 CD2v suppresses type I IFN production and IFN-stimulated genes expression through negatively regulating cGMP-AMP synthase …

…, S Dong, X Liu, C Feng, S Cao, G Ye… - The Journal of …, 2023 - journals.aai.org
African swine fever is a fatal infectious disease caused by African swine fever virus (ASFV).
The high mortality caused by this infectious disease is a significant challenge to the swine …

Deletion of African swine fever virus (ASFV) H240R gene attenuates the virulence of ASFV by enhancing NLRP3-mediated inflammatory responses

L Huang, H Liu, G Ye, X Liu, W Chen, Z Wang… - Journal of …, 2023 - Am Soc Microbiol
African swine fever (ASF) is a highly contagious infectious disease of domestic pigs and
wild boars caused by African swine fever virus (ASFV), with a mortality rate of up to 100%. In …

[PDF][PDF] Vimentin inhibits type I interferon production by disrupting the TBK1-IKKε-IRF3 axis

H Liu, G Ye, X Liu, M Xue, Q Zhou, L Zhang, K Zhang… - Cell Reports, 2022 - cell.com
Cytoskeleton proteins have been reported to be involved in the host antiviral immune
responses. However, how cytoskeleton proteins regulate host antiviral immune responses is not …

African swine fever virus pE301R negatively regulates cGAS-STING signaling pathway by inhibiting the nuclear translocation of IRF3

X Liu, H Liu, G Ye, M Xue, H Yu, C Feng, Q Zhou… - Veterinary …, 2022 - Elsevier
African swine fever (ASF) is a highly contagious and lethal infectious disease of domestic
pigs and wild boars by the African swine fever virus (ASFV). ASFV infects domestic pigs with …

Pseudorabies virus infection activates the TLR-NF-κB Axis and AIM2 inflammasome to enhance inflammatory responses in mice

Q Zhou, L Zhang, Q Lin, H Liu, G Ye, X Liu… - Journal of …, 2023 - Am Soc Microbiol
Pseudorabies virus (PRV) infection activates inflammatory responses to release robust
proinflammatory cytokines, which are critical for controlling viral infection and clearance of PRV. …

[HTML][HTML] Isolation and characterization of two pseudorabies virus and evaluation of their effects on host natural immune responses and pathogenicity

Q Zhou, L Zhang, H Liu, G Ye, L Huang, C Weng - Viruses, 2022 - mdpi.com
Pseudorabies, caused by the pseudorabies virus (PRV), is an acute fatal disease, which
can infect rodents, mammals, and other livestock and wild animals across species. Recently, …

[HTML][HTML] African swine fever virus pB318L, a trans-geranylgeranyl-diphosphate synthase, negatively regulates cGAS-STING and IFNAR-JAK-STAT signaling pathways

X Liu, H Chen, G Ye, H Liu, C Feng, W Chen… - Plos …, 2024 - journals.plos.org
African swine fever (ASF) is an acute, hemorrhagic, and severe infectious disease caused
by the ASF virus (ASFV). ASFV has evolved multiple strategies to escape host antiviral …

Porcine reproductive and respiratory syndrome virus infection inhibits NF-κB signaling pathway through cleavage of IKKβ by Nsp4

…, M Xue, Q Zhou, L Zhang, X Liu, C Feng, G Ye… - Veterinary …, 2023 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) is a highly contagious porcine
pathogen that causes serious economic losses to the world swine industry. The inhibitor …