User profiles for Guanhong Bu

Guanhong Bu

Postdoctoral scholar, University of California, Los Angeles
Verified email at g.ucla.edu
Cited by 170

Crystal structure and orientation of organic semiconductor thin films by microcrystal electron diffraction and grazing-incidence wide-angle X-ray scattering

AM Levine, G Bu, S Biswas, EHR Tsai… - Chemical …, 2020 - pubs.rsc.org
We use microcrystal electron diffraction (MicroED) to determine structures of three organic
semiconductors, and show that these structures can be used along with grazing-incidence …

MicroED as a powerful tool for structure determination of macrocyclic drug compounds directly from their powder formulations

E Danelius, G Bu, LHE Wieske, T Gonen - ACS Chemical Biology, 2023 - ACS Publications
Macrocycles are important drug leads with many advantages including the ability to target flat
and featureless binding sites as well as to act as molecular chameleons and thereby reach …

MicroED for the study of protein–ligand interactions and the potential for drug discovery

LJ Clark, G Bu, BL Nannenga, T Gonen - Nature Reviews Chemistry, 2021 - nature.com
Microcrystal electron diffraction (MicroED) is an electron cryo-microscopy (cryo-EM) technique
used to determine molecular structures with crystals that are a millionth the size needed …

Beam-sensitive metal-organic framework structure determination by microcrystal electron diffraction

F Banihashemi, G Bu, A Thaker, D Williams, JYS Lin… - Ultramicroscopy, 2020 - Elsevier
Abstract Analysis of metal-organic framework (MOF) structure by electron microscopy and
electron diffraction offers an alternative to growing large single crystals for high-resolution X-…

[HTML][HTML] The evolution and the advantages of MicroED

BL Nannenga, G Bu, D Shi - Frontiers in Molecular Biosciences, 2018 - frontiersin.org
MicroED is a method which combines cryo-EM sample preparation and instrumentation, with
electron and X-ray crystallography data analysis, and it has been employed to solve many …

[PDF][PDF] Structure determination from lipidic cubic phase embedded microcrystals by MicroED

L Zhu, G Bu, L Jing, D Shi, MY Lee, T Gonen, W Liu… - Structure, 2020 - cell.com
The lipidic cubic phase (LCP) technique has proved to facilitate the growth of high-quality
crystals that are otherwise difficult to grow by other methods. However, the crystal size …

[HTML][HTML] Recent developments toward integrated metabolomics technologies (UHPLC-MS-SPE-NMR and MicroED) for higher-throughput confident metabolite …

R Ghosh, G Bu, BL Nannenga… - Frontiers in Molecular …, 2021 - frontiersin.org
Metabolomics has emerged as a powerful discipline to study complex biological systems
from a small molecule perspective. The success of metabolomics hinges upon reliable …

Producing nitrite from anodic ammonia oxidation to accelerate anammox in a bioelectrochemical system with a given anode potential

T Zhu, Y Zhang, G Bu, X Quan, Y Liu - Chemical Engineering Journal, 2016 - Elsevier
Requirement of NO 2 − presence in feed is one barrier of anammox process for the application
since NO 2 − is not a frequent composition in most wastewaters. In this study, anodic …

Efficient free triplet generation follows singlet fission in diketopyrrolopyrrole polymorphs with goldilocks coupling

AM Levine, G He, G Bu, P Ramos, F Wu… - The Journal of …, 2021 - ACS Publications
Microcrystal electron diffraction, grazing incidence wide-angle scattering, and UV–vis
spectroscopy were used to determine the unit-cell structure and the relative composition of …

MicroED sample preparation and data collection for protein crystals

G Bu, BL Nannenga - cryoEM: Methods and Protocols, 2021 - Springer
Microcrystal Electron Diffraction (MicroED) enables structure determination of very small
crystals that are much too small to be of use for other conventional diffraction techniques. …