Diabetic kidney disease (DKD) is the leading cause of morbidity and mortality in diabetic
patients. Defining risk factors for DKD using a reductionist approach has proven challenging. …

Ketosis, characterized by high concentrations of ketone bodies in the blood, urine, and milk,
affects a considerable number of cows immediately after calving. Although much is known …

The objective of this investigation was to search for alterations in blood variables related to
innate immunity and carbohydrate and lipid metabolism during the transition period in cows …

Comprehensive and spatially mapped molecular atlases of organs at a cellular level are a
critical resource to gain insights into pathogenic mechanisms and personalized therapies for …

The Yangtze River Basin (YRB) is a region of vital economic and ecological importance in
China, facing challenges of water scarcity and flooding underpinned by complex, yet …

Background Failure to expel fetal membranes within 24 h of calving is a pathological condition
defined as retained placenta (RP). The objective of this investigation was to evaluate …

Diabetic kidney disease (DKD) can lead to end-stage kidney disease (ESKD) and mortality;
however, few mechanistic biomarkers are available for high-risk patients, especially those …

The overall purpose of the present study was to search for early screening biomarkers of
disease state. Therefore the objectives of this study were to evaluate metabolites related to …

In this paper, cyclic expansion extrusion with an asymmetrical extrusion cavity (CEE-AEC)
was proposed as a novel severe plastic deformation process for fabricating bulk ultrafine-…

Kidney Precision Medicine Project (KPMP) is building a spatially specified human kidney
tissue atlas in health and disease with single-cell resolution. Here, we describe the …