To the Editor: Zika virus (ZIKV) is a mosquitoborne flavivirus related to yellow fever virus,
dengue virus (DENV), and West Nile virus (WNV). It is a single-stranded positive RNA virus (…

1These authors contributed equally to this article. outbreaks were reported from Yap Island in
2007 (1), French Polynesia in 2013 (2), and Cook Island and New Caledonia in 2014 (3). It …

Zika virus (ZIKV) infection has been associated with severe complications both in the
developing and adult nervous system. To investigate the deleterious effects of ZIKV infection, we …

Metagenomic next-generation sequencing (mNGS) of samples from 15 patients with documented
Zika virus (ZIKV) infection in Bahia, Brazil, from April 2015 to January 2016 identified …

Background Since their emergence in the Americas, chikungunya (CHIKV) and Zika (ZIKV)
viruses co-circulate with dengue virus (DENV), hampering clinical diagnosis. We investigated …

Several months after the introduction of Zika virus into northeastern Brazil, obstetricians
noticed an increased number of fetuses with congenital malformations during ultrasound …

Zika and dengue viruses are closely related flaviviruses, with immunological interactions and
identical urban, mosquito-borne transmission. 1 Therefore, the recent introduction of Zika …

… to the manufacturer’s instructions for semiquantitative … Positive and negative controls were
provided by the test’s … appropriate credit to the original author(s) and the source, provide a link …

Sequencing of isolates from patients in Bahia, Brazil, where most Zika virus cases in Brazil
have been reported, resulted in 11 whole and partial Zika virus genomes. Phylogenetic …

We conducted an external quality assessment of Zika virus molecular diagnostic tests in
Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and …