[HTML][HTML] Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Y Peng, AJ Mentzer, G Liu, X Yao, Z Yin, D Dong… - Nature …, 2020 - nature.com
The development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines
and therapeutics will depend on understanding viral immunity. We studied T cell memory …
and therapeutics will depend on understanding viral immunity. We studied T cell memory …
[HTML][HTML] An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease
…, D Dong, F Penkava, AJ Mentzer, X Yao, G Liu… - Nature …, 2022 - nature.com
NP 105–113 -B*07:02-specific CD8 + T cell responses are considered among the most
dominant in SARS-CoV-2-infected individuals. We found strong association of this response with …
dominant in SARS-CoV-2-infected individuals. We found strong association of this response with …
[PDF][PDF] The impact of viral mutations on recognition by SARS-CoV-2 specific T cells
We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating
global sequence data. Several variants within nucleocapsid and ORF3a epitopes have …
global sequence data. Several variants within nucleocapsid and ORF3a epitopes have …
[HTML][HTML] Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity
…, SD Draganov, I Vendrell, G Liu… - Nature …, 2024 - nature.com
Cancer remains one of the leading causes of mortality worldwide, leading to increased
interest in utilizing immunotherapy strategies for better cancer treatments. In the past decade, …
interest in utilizing immunotherapy strategies for better cancer treatments. In the past decade, …
[PDF][PDF] Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection
T cell responses precede antibody and may provide early control of infection. We analyzed
the clonal basis of this rapid response following SARS-COV-2 infection. We applied T cell …
the clonal basis of this rapid response following SARS-COV-2 infection. We applied T cell …
[PDF][PDF] Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination
…, Y Lu, B Wang, L Godfrey, AJ Mentzer, X Yao, G Liu… - Cell reports, 2023 - cell.com
Most existing studies characterizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific
T cell responses are peptide based. This does not allow evaluation of …
T cell responses are peptide based. This does not allow evaluation of …
[HTML][HTML] Distinct tumour antigen-specific T-cell immune response profiles at different hepatocellular carcinoma stages
C Zang, Y Zhao, L Qin, G Liu, J Sun, K Li, Y Zhao… - BMC cancer, 2021 - Springer
Background Cancer-testis antigens (CTAs) and tumour-associated antigens (TAAs) are
frequently expressed in hepatocellular carcinoma (HCC); however, the role of tumour-antigen-…
frequently expressed in hepatocellular carcinoma (HCC); however, the role of tumour-antigen-…
Exploring the spatial–temporal evolution and driving mechanisms for coupling coordination between green transformation of urban construction land and industrial …
F Cui, Y Wang, G Liu - Environmental Science and Pollution Research, 2023 - Springer
With the acceleration of urbanization and industrialization, the increasingly prominent
contradiction between urban industrial development and urban land supply and demand …
contradiction between urban industrial development and urban land supply and demand …
[HTML][HTML] Variations in dynamic tumor-associated antigen-specific T cell responses correlate with HCC recurrence after thermal ablation
C Zang, Y Zhao, G Liu, K Li, L Qin, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Ablative therapy is a recommended treatment for hepatocellular carcinoma (HCC)
not only for its effective eradication of tumors, but also for its induction of host immunity. …
not only for its effective eradication of tumors, but also for its induction of host immunity. …
[HTML][HTML] The signature of HBV-related liver disease in peripheral blood mononuclear cell DNA methylation
K Li, L Qin, S Jiang, A Li, C Zhang, G Liu, J Sun… - Clinical …, 2020 - Springer
Background Hepatitis B virus (HBV)-related liver disease induces liver damage by hepatic
immune and inflammatory response. The association between aberrant peripheral blood …
immune and inflammatory response. The association between aberrant peripheral blood …