Forced G1-phase reduction alters mode of division, neuron number, and laminar phenotype in the cerebral cortex

LJ Pilaz, D Patti, G Marcy, E Ollier… - Proceedings of the …, 2009 - National Acad Sciences
The link between cortical precursors G1 duration (TG1) and their mode of division remains a
major unresolved issue of potential importance for regulating corticogenesis. Here, we …

Cell cycle features of primate embryonic stem cells

AC Fluckiger, G Marcy, M Marchand, D Négre… - Stem …, 2006 - academic.oup.com
Using flow cytometry measurements combined with quantitative analysis of cell cycle
kinetics, we show that rhesus monkey embryonic stem cells (ESCs) are characterized by an …

Microarray with micro‐and nano‐topographies enables identification of the optimal topography for directing the differentiation of primary murine neural progenitor cells

AAK Moe, M Suryana, G Marcy, SK Lim, S Ankam… - Small, 2012 - Wiley Online Library
During development and tissue repair, progenitor cells are guided by both biochemical and
biophysical cues of their microenvironment, including topographical signals. The …

[HTML][HTML] Taurine induces proliferation of neural stem cells and synapse development in the developing mouse brain

MC Shivaraj, G Marcy, G Low, JR Ryu, X Zhao… - 2012 - journals.plos.org
Taurine is a sulfur-containing amino acid present in high concentrations in mammalian
tissues. It has been implicated in several processes involving brain development and …

[HTML][HTML] Pharmacogenomic identification of small molecules for lineage specific manipulation of subventricular zone germinal activity

K Azim, D Angonin, G Marcy, F Pieropan, A Rivera… - PLoS …, 2017 - journals.plos.org
Strategies for promoting neural regeneration are hindered by the difficulty of manipulating
desired neural fates in the brain without complex genetic methods. The subventricular zone (…

Single-cell analysis of the postnatal dorsal V-SVZ reveals a role for Bmpr1a signaling in silencing pallial germinal activity

G Marcy, L Foucault, E Babina, T Capeliez… - Science …, 2023 - science.org
The ventricular-subventricular zone (V-SVZ) is the largest neurogenic region of the postnatal
forebrain, containing neural stem cells (NSCs) that emerge from both the embryonic pallium …

[PDF][PDF] Apoptosis, G1 phase stall, and premature differentiation account for low chimeric competence of human and rhesus monkey naive pluripotent stem cells

I Aksoy, C Rognard, A Moulin, G Marcy, E Masfaraud… - Stem cell reports, 2021 - cell.com
After reprogramming to naive pluripotency, human pluripotent stem cells (PSCs) still exhibit
very low ability to make interspecies chimeras. Whether this is because they are inherently …

[PDF][PDF] HOPX defines heterogeneity of postnatal subventricular zone neural stem cells

S Zweifel, G Marcy, QL Guidice, D Li, C Heinrich… - Stem cell reports, 2018 - cell.com
The largest diversity of neural lineages generated from the subventricular zone (SVZ) occurs
early after birth and is regulated in a spatiotemporal manner depending on the expression …

[HTML][HTML] Chemogenetic activation of prefrontal astroglia enhances recognition memory performance in rat

…, O Dkhissi-Benyahya, C Heinrich, G Marcy… - Biomedicine & …, 2023 - Elsevier
Prefrontal cortex (PFC) inputs to the hippocampus are supposed to be critical in memory
processes. Astrocytes are involved in several brain functions, such as homeostasis, …

Derivation and cloning of a novel rhesus embryonic stem cell line stably expressing tau-green fluorescent protein

F Wianny, A Bernat, C Huissoud, G Marcy… - Stem Cells, 2008 - academic.oup.com
Embryonic stem cells (ESC) have the ability of indefinite self-renewal and multilineage
differentiation, and they carry great potential in cell-based therapies. The rhesus macaque is the …