Extracellular vesicles are a heterogeneous group of cell-derived membranous structures
comprising exosomes and microvesicles, which originate from the endosomal system or which …

Exosomes are membrane vesicles that are released by cells upon fusion of multivesicular
bodies with the plasma membrane. Their molecular composition reflects their origin in …

Extracellular vesicles (EVs) are released by most cell types but providing evidence for their
physiological relevance remains challenging due to a lack of appropriate model organisms. …

Extracellular vesicles (EVs) are increasingly recognized as important mediators of intercellular
communication. They have important roles in numerous physiological and pathological …

Extracellular vesicles (EVs) are nano-sized lipid bilayer vesicles released by virtually every
cell type. EVs have diverse biological activities, ranging from roles in development and …

Information exchange executed by extracellular vesicles, including exosomes, is a newly
described form of intercellular communication important in the development and physiology of …

Background & Aims: Given the observations that intestinal epithelial cells (IECs) can present
antigens to CD4 + T lymphocytes and that professional antigen-presenting cells secrete …

Celiac disease (CD) is an enteropathy resulting from an abnormal immune response to
gluten-derived peptides in genetically susceptible individuals. This immune response is initiated …

Exosomes are extracellular vesicles (EVs) secreted upon fusion of endosomal multivesicular
bodies (MVBs) with the plasma membrane. The mechanisms involved in their biogenesis …

Cargo sorting to intraluminal vesicles (ILVs) of multivesicular endosomes is required for
lysosome-related organelle (LRO) biogenesis. PMEL—a component of melanocyte LROs (…