Long non-coding RNAs (lncRNAs) are a family of heterogeneous RNAs that play major roles
in multiple biological processes. We recently identified an extended repertoire of more than …

The keratin 16 gene (KRT16) encodes an intermediate filament protein mainly expressed in
palmoplantar epidermis. In humans, mutations in KRT16 are responsible for pachyonychia …

Dogs have an exquisite sense of olfaction. In many instances this ability has been utilized by
humans for a wide range of important situations including detecting explosives and illegal …

Dogs have an exquisite sense of olfaction. In many instances this ability has been put to use
by humans in a wide range of important situations. It is also thought that some breeds have …

These results led us to analyze 2 cases for which brain tissue had been collected. We identified
a BRAF-MBP gene fusion in one case using RNAseq and we are currently checking for …

… Anne Sophie Grandoulier, MSc, Claire Vilain, MD, and Philippe Picaut, PharmD … The authors
thank the participants and their families and Sylvie Guillory (… Anne Sophie Grandoulier, MSc …

Under physiological conditions, cAMP signaling plays a key role in the regulation of cardiac
function. Activation of this intracellular signaling pathway mirrors cardiomyocyte adaptation …

Canine cancers represent a tremendous natural resource due to their incidence and striking
similarities to human cancers, sharing similar clinical and pathologic features as well as …

In humans, hereditary sensory neuropathies (HSN), also known as hereditary sensory and
autonomic neuropathies (HSAN), constitute a clinically and genetically heterogeneous group …

We report two series of individuals with DDX3X variations, one (48 individuals) from physicians
and one (44 individuals) from caregivers. These two series include several symptoms in …