The auxin-inducible degron (AID) system has emerged as a powerful tool to conditionally
deplete proteins in a range of organisms and cell types. Here, we describe a toolkit to augment …

As developmental biologists in the age of genome editing, we now have access to an ever-increasing
array of tools to manipulate endogenous gene expression. The auxin-inducible …

In sexually reproducing metazoans, spermatogenesis is the process by which uncommitted
germ cells give rise to haploid sperm. Work in model systems has revealed mechanisms …

Synapsis involves the assembly of a proteinaceous structure, the synaptonemal complex (SC),
between paired homologous chromosomes, and is essential for proper meiotic …

The auxin-inducible degron (AID) system has emerged as a powerful tool to conditionally
deplete proteins in a range of organisms and cell-types. Here, we describe a toolkit to augment …

Circadian rhythms are endogenous oscillations present in nearly all organisms from prokaryotes
to humans, allowing them to adapt to cyclical environments close to 24 hours. Circadian …

C. elegans NHR-85 is a poorly characterized nuclear hormone receptor transcription factor
with an emerging role in regulating microRNA expression to control developmental timing. …

All living organisms have biological clocks that drive and coordinate repetitive developmental
processes. These intrinsic timing devices are essential for animal development and …

As developmental biologists in the age of genome editing, we now have access to an ever-increasing
array of tools to manipulate endogenous gene expression. By combining CRISPR/…

As developmental biologists in the age of genome editing, we now have access to an
everincreasing array of tools to manipulate endogenous gene expression. The auxin-inducible …