[HTML][HTML] CRISPR–Cas12-based detection of SARS-CoV-2

JP Broughton, X Deng, G Yu, CL Fasching… - Nature …, 2020 - nature.com
An outbreak of betacoronavirus severe acute respiratory syndrome (SARS)-CoV-2 began in
Wuhan, China in December 2019. COVID-19, the disease associated with SARS-CoV-2 …

Functional genomic analysis of the AUXIN RESPONSE FACTOR gene family members in Arabidopsis thaliana: unique and overlapping functions of ARF7 and ARF19

…, D Nguyen, C Onodera, H Quach, A Smith, G Yu… - The Plant …, 2005 - academic.oup.com
The AUXIN RESPONSE FACTOR (ARF) gene family products, together with the AUXIN/INDOLE-3-ACETIC
ACID proteins, regulate auxin-mediated transcriptional activation/repression. …

Empirical Analysis of Transcriptional Activity in the Arabidopsis Genome

…, SX Liu, B Lam, H Sakano, T Wu, G Yu… - science, 2003 - science.org
Functional analysis of a genome requires accurate gene structure information and a complete
gene inventory. A dual experimental strategy was used to verify and correct the initial …

[HTML][HTML] Actionable diagnosis of neuroleptospirosis by next-generation sequencing

…, E Samayoa, M Biagtan, H Bashir, G Yu… - … England Journal of …, 2014 - Mass Medical Soc
<p id="p001">A 14-year-old boy with severe combined immunodeficiency presented three
times to a medical facility over a period of 4 months with fever and headache that progressed …

Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids

…, A Gopez, K Reyes, K Zorn, H Sample, G Yu… - Nature medicine, 2021 - nature.com
We developed a metagenomic next-generation sequencing (mNGS) test using cell-free DNA
from body fluids to identify pathogens. The performance of mNGS testing of 182 body fluids …

[HTML][HTML] Clinical metagenomic sequencing for diagnosis of meningitis and encephalitis

…, HA Sample, KC Zorn, S Arevalo, G Yu… - … England Journal of …, 2019 - Mass Medical Soc
Background Metagenomic next-generation sequencing (NGS) of cerebrospinal fluid (CSF)
has the potential to identify a broad range of pathogens in a single test. Methods In a 1-year, …

[HTML][HTML] Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis

AL Greninger, SN Naccache, S Federman, G Yu… - Genome medicine, 2015 - Springer
We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus (EBOV),
and hepatitis C virus (HCV) from four human blood samples by MinION nanopore …

Functional Genomic Analysis of the AUXIN/INDOLE-3-ACETIC ACID Gene Family Members in Arabidopsis thaliana

…, A Liu, C Onodera, H Quach, A Smith, G Yu… - The Plant …, 2005 - academic.oup.com
Auxin regulates various aspects of plant growth and development. The AUXIN/INDOLE-3-ACETIC
ACID (Aux/IAA) genes encode short-lived transcriptional repressors that are targeted …

A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012–14): a retrospective cohort study

…, K Messacar, A Clayton, G Yu… - The Lancet Infectious …, 2015 - thelancet.com
Background Enterovirus D68 was implicated in a widespread outbreak of severe respiratory
illness across the USA in 2014 and has also been reported sporadically in patients with …

[HTML][HTML] Nanopore DNA sequencing and genome assembly on the International Space Station

…, D Stryke, S Somasekar, N Alexander, G Yu… - Scientific reports, 2017 - nature.com
We evaluated the performance of the MinION DNA sequencer in-flight on the International
Space Station (ISS), and benchmarked its performance off-Earth against the MinION, Illumina …