[HTML][HTML] A nuclear function of β-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription
Chromatin modification is considered to be a fundamental mechanism of regulating gene
expression to generate coordinated responses to environmental changes, however, whether it …
expression to generate coordinated responses to environmental changes, however, whether it …
Modification of hippocampal neurogenesis and neuroplasticity by social environments
L Lu, G Bao, H Chen, P Xia, X Fan, J Zhang, G Pei… - Experimental …, 2003 - Elsevier
Synaptic plasticity and neurogenesis in the brain are affected by environmental stimuli. The
present study was designed to investigate the effects of social environments on learning and …
present study was designed to investigate the effects of social environments on learning and …
Activation of β2-adrenergic receptor stimulates γ-secretase activity and accelerates amyloid plaque formation
Y Ni, X Zhao, G Bao, L Zou, L Teng, Z Wang, M Song… - Nature medicine, 2006 - nature.com
Amyloid plaque is the hallmark and primary cause of Alzheimer disease. Mutations of
presenilin-1, the γ-secretase catalytic subunit, can affect amyloid-β (Aβ) production and Alzheimer …
presenilin-1, the γ-secretase catalytic subunit, can affect amyloid-β (Aβ) production and Alzheimer …
[PDF][PDF] Human brain organoids assemble functionally integrated bilateral optic vesicles
…, A Mariappan, F Schinzel, CM Karch, G Bao… - Cell Stem Cell, 2021 - cell.com
During embryogenesis, optic vesicles develop from the diencephalon via a multistep
process of organogenesis. Using induced pluripotent stem cell (iPSC)-derived human brain …
process of organogenesis. Using induced pluripotent stem cell (iPSC)-derived human brain …
[HTML][HTML] Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids
MP Zafeiriou, G Bao, J Hudson, R Halder… - Nature …, 2020 - nature.com
Brain organoids are promising tools for disease modeling and drug development. For proper
neuronal network formation excitatory and inhibitory neurons as well as glia need to co-…
neuronal network formation excitatory and inhibitory neurons as well as glia need to co-…
[HTML][HTML] Morphine and heroin differentially modulate in vivo hippocampal LTP in opiate-dependent rat
Addictive drugs have been shown to severely influence many neuronal functions, which are
considered as the underlying mechanisms for physiological and psychological dependences…
considered as the underlying mechanisms for physiological and psychological dependences…
Hippocampal long-term potentiation is reduced by chronic opiate treatment and can be restored by re-exposure to opiates
L Pu, GB Bao, NJ Xu, L Ma, G Pei - Journal of Neuroscience, 2002 - Soc Neuroscience
Chronic exposure to opiates eventually leads to drug addiction, which is believed to involve
maladaptive changes in brain function, but the underlying neuronal mechanisms remain …
maladaptive changes in brain function, but the underlying neuronal mechanisms remain …
[HTML][HTML] Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R
…, V Kluever, P Agüi-Gonzalez, K Grewe, G Bao… - Nature …, 2021 - nature.com
The brain extracellular matrix (ECM) consists of extremely long-lived proteins that assemble
around neurons and synapses, to stabilize them. The ECM is thought to change only rarely, …
around neurons and synapses, to stabilize them. The ECM is thought to change only rarely, …
[HTML][HTML] Stimulation-and palmitoylation-dependent changes in oligomeric conformation of serotonin 5-HT1A receptorsi
…, A Woehler, J Wlodarczyk, E Papusheva, G Bao… - … et Biophysica Acta (BBA …, 2008 - Elsevier
In the present study we analyzed the oligomerization state of the serotonin 5-HT1A receptor
and studied oligomerization dynamics in living cells. We also investigated the role of …
and studied oligomerization dynamics in living cells. We also investigated the role of …
Secondary ion mass spectrometry imaging reveals changes in the lipid structure of the plasma membranes of hippocampal neurons following drugs affecting neuronal …
P Agüi-Gonzalez, B Guobin… - ACS Chemical …, 2021 - ACS Publications
The cellular functions of lipids in the neuronal plasma membranes have been increasingly
acknowledged, particularly their association to neuronal processes and synaptic plasticity. …
acknowledged, particularly their association to neuronal processes and synaptic plasticity. …