User profiles for Guoli Shi

Guoli Shi

NIH/NCI
Verified email at nih.gov
Cited by 648

Opposing activities of IFITM proteins in SARS‐CoV‐2 infection

G Shi, AD Kenney, E Kudryashova, A Zani… - The EMBO …, 2021 - embopress.org
Interferon‐induced transmembrane proteins (IFITMs) restrict infections by many viruses, but
a subset of IFITMs enhance infections by specific coronaviruses through currently unknown …

Microtubules underlie dysfunction in duchenne muscular dystrophy

RJ Khairallah, G Shi, F Sbrana, BL Prosser… - Science …, 2012 - science.org
Duchenne muscular dystrophy (DMD) is a fatal X-linked degenerative muscle disease
caused by the absence of the microtubule-associated protein dystrophin, which results in a …

[HTML][HTML] A monofluoride ether-based electrolyte solution for fast-charging and low-temperature non-aqueous lithium metal batteries

…, J Chang, L Wang, J Li, C Wang, R Wang, G Shi… - Nature …, 2023 - nature.com
The electrochemical stability window of the electrolyte solution limits the energy content of
non-aqueous lithium metal batteries. In particular, although electrolytes comprising fluorinated …

[HTML][HTML] Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle

JP Kerr, P Robison, G Shi, AI Bogush… - Nature …, 2015 - nature.com
In striated muscle, X-ROS is the mechanotransduction pathway by which mechanical stress
transduced by the microtubule network elicits reactive oxygen species. X-ROS tunes Ca 2+ …

[HTML][HTML] More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins

G Shi, O Schwartz, AA Compton - Retrovirology, 2017 - Springer
The first responders of human antiviral immunity are components of the intrinsic immune
response that reside within each and every one of our cells. This cell-autonomous arsenal …

A bifunctional fluorinated ether co-solvent for dendrite-free and long-term lithium metal batteries

G Zhang, X Deng, J Li, J Wang, G Shi, Y Yang, J Chang… - Nano Energy, 2022 - Elsevier
The employment of localized high concentration electrolytes (LHCEs) has been demonstrated
as an effective strategy for the fabrication of next-generation high-energy-density lithium …

[HTML][HTML] Omicron Spike confers enhanced infectivity and interferon resistance to SARS-CoV-2 in human nasal tissue

G Shi, T Li, KK Lai, RF Johnson, JW Yewdell… - Nature …, 2024 - nature.com
Omicron emerged following COVID-19 vaccination campaigns, displaced previous SARS-CoV-2
variants of concern worldwide, and gave rise to lineages that continue to spread. Here, …

Microtubules tune mechanotransduction through NOX2 and TRPV4 to decrease sclerostin abundance in osteocytes

…, HC Joca, RA Law, KM Williams, JP Kerr, G Shi… - Science …, 2017 - science.org
The adaptation of the skeleton to its mechanical environment is orchestrated by mechanosensitive
osteocytes, largely by regulating the abundance of sclerostin, a secreted inhibitor of …

mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3

G Shi, S Ozog, BE Torbett… - Proceedings of the …, 2018 - National Acad Sciences
Rapamycin and its derivatives are specific inhibitors of mammalian target of rapamycin (mTOR)
kinase and, as a result, are well-established immunosuppressants and antitumorigenic …

Single-color, ratiometric biosensors for detecting signaling activities in live cells

BL Ross, B Tenner, ML Markwardt, A Zviman, G Shi… - Elife, 2018 - elifesciences.org
Genetically encoded fluorescent biosensors have revolutionized the study of signal transduction
by enabling the real-time tracking of signaling activities in live cells. Investigating the …