User profiles for Gustavo A Rodriguez

Gustavo A Rodriguez

Associate Research Scientist, Columbia University
Verified email at cumc.columbia.edu
Cited by 2032

Neuronal activity enhances tau propagation and tau pathology in vivo

JW Wu, SA Hussaini, IM Bastille, GA Rodriguez… - Nature …, 2016 - nature.com
Tau protein can transfer between neurons transneuronally and trans-synaptically, which is
thought to explain the progressive spread of tauopathy observed in the brain of patients with …

Ovarian cancer: etiology, risk factors, and epidemiology

J Hunn, GC Rodriguez - Clinical obstetrics and gynecology, 2012 - journals.lww.com
Little is known regarding the early aspects of ovarian carcinogenesis. As a consequence,
the identification of women at risk for the disease is based primarily on clinical grounds, with …

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general …

…, T Rebbeck, JL Blum, M Piedmonte, GC Rodriguez… - Nature …, 2010 - nature.com
Germline BRCA1 mutations predispose to breast cancer. To identify genetic modifiers of this
risk, we performed a genome-wide association study in 1,193 individuals with BRCA1 …

Distribution of SUN, OVATE, LC, and FAS in the Tomato Germplasm and the Relationship to Fruit Shape Diversity

GR Rodriguez, S Muños, C Anderson, SC Sim… - Plant …, 2011 - academic.oup.com
Phenotypic diversity within cultivated tomato (Solanum lycopersicum) is particularly evident
for fruit shape and size. Four genes that control tomato fruit shape have been cloned. SUN …

[HTML][HTML] The chemical interactions underlying tomato flavor preferences

…, A Blandon-Ubeda, D Bies, AZ Odabasi, GR Rodríguez… - Current biology, 2012 - cell.com
Although human perception of food flavors involves integration of multiple sensory inputs,
the most salient sensations are taste and olfaction [1]. Ortho- and retronasal olfaction are …

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

…, K Claes, K De Leeneer, J Kirk, GC Rodriguez… - Nature …, 2015 - nature.com
Genome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer (EOC)
susceptibility alleles. The pattern of association at these loci is consistent in BRCA1 and …

[PDF][PDF] Tau pathology induces excitatory neuron loss, grid cell dysfunction, and spatial memory deficits reminiscent of early Alzheimer's disease

H Fu, GA Rodriguez, M Herman, S Emrani, E Nahmani… - Neuron, 2017 - cell.com
The earliest stages of Alzheimer's disease (AD) are characterized by the formation of mature
tangles in the entorhinal cortex and disorientation and confusion when navigating familiar …

Effect of progestin on the ovarian epithelium of macaques: cancer prevention through apoptosis?

GC Rodriguez, DK Walmer, M Cline… - Journal of the …, 1998 - journals.sagepub.com
Objective: The apoptosis pathway is a vital mechanism in vivo that functions to eradicate
genetically damaged cells prone to malignancy. The purpose of this study was to determine …

Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction

…, A Dutra-Clarke, M Piedmonte, GC Rodriguez… - Cancer research, 2010 - AACR
The known breast cancer susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1,
LSP1, and 2q35 confer increased risks of breast cancer for BRCA1 or BRCA2 mutation …

Prospects for the biological control of Drosophila suzukii

R Gabarra, J Riudavets, GA Rodríguez, J Pujade-Villar… - BioControl, 2015 - Springer
The invasive pest Drosophila suzukii (Matsumura) (Diptera: Drosophilidae) causes serious
economic damage in several soft fruit crops. This study aimed (1) to identify naturally …