Mechanism of eukaryotic homologous recombination
J San Filippo, P Sung, H Klein - Annu. Rev. Biochem., 2008 - annualreviews.org
… the 3′ end of the invading strand, (f) capture of the second DSB end by annealing to the
extended D loop, (g) formation of two crossed strand or Holliday junctions (HJ)s, and lastly (h) …
extended D loop, (g) formation of two crossed strand or Holliday junctions (HJ)s, and lastly (h) …
Mechanism of homologous recombination: mediators and helicases take on regulatory functions
P Sung, H Klein - Nature reviews Molecular cell biology, 2006 - nature.com
Homologous recombination (HR) is an important mechanism for the repair of damaged
chromosomes, for preventing the demise of damaged replication forks, and for several other …
chromosomes, for preventing the demise of damaged replication forks, and for several other …
Learning in the twenty-first-century workplace
Human capital resources are key for organizations to gain a competitive advantage. Learning
based on formal training and development programs, informal learning, and knowledge …
based on formal training and development programs, informal learning, and knowledge …
[HTML][HTML] Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia
…, JP Daubert, SL Higgins, H Klein… - … England Journal of …, 1996 - Mass Medical Soc
Background Unsustained ventricular tachycardia in patients with previous myocardial infarction
and left ventricular dysfunction is associated with a two-year mortality rate of about 30 …
and left ventricular dysfunction is associated with a two-year mortality rate of about 30 …
[HTML][HTML] Cardiac-resynchronization therapy for the prevention of heart-failure events
AJ Moss, WJ Hall, DS Cannom, H Klein… - … England Journal of …, 2009 - Mass Medical Soc
Background This trial was designed to determine whether cardiac-resynchronization therapy
(CRT) with biventricular pacing would reduce the risk of death or heart-failure events in …
(CRT) with biventricular pacing would reduce the risk of death or heart-failure events in …
A set of principles for conducting and evaluating interpretive field studies in information systems
HK Klein, MD Myers - MIS quarterly, 1999 - JSTOR
This article discusses the conduct and evaluation of interpretive research in information
systems. While the conventions for evaluating information systems case studies conducted …
systems. While the conventions for evaluating information systems case studies conducted …
[HTML][HTML] Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction
AJ Moss, W Zareba, WJ Hall, H Klein… - … England Journal of …, 2002 - Mass Medical Soc
Background Patients with reduced left ventricular function after myocardial infarction are at
risk for life-threatening ventricular arrhythmias. This randomized trial was designed to …
risk for life-threatening ventricular arrhythmias. This randomized trial was designed to …
[HTML][HTML] Landscape of genetic lesions in 944 patients with myelodysplastic syndromes
…, K Chiba, H Tanaka, HP Koeffler, HU Klein… - Leukemia, 2014 - nature.com
High-throughput DNA sequencing significantly contributed to diagnosis and prognostication
in patients with myelodysplastic syndromes (MDS). We determined the biological and …
in patients with myelodysplastic syndromes (MDS). We determined the biological and …
Organizational socialization: Its content and consequences.
…, AM O'Leary-Kelly, S Wolf, HJ Klein… - Journal of Applied …, 1994 - psycnet.apa.org
Content dimensions of the socialization domain were defined to determine relationships
between learning particular features of a job/organization and the process and outcomes of …
between learning particular features of a job/organization and the process and outcomes of …
[HTML][HTML] Reduction in inappropriate therapy and mortality through ICD programming
…, WJ Hall, DT Huang, J Kautzner, H Klein… - … England Journal of …, 2012 - Mass Medical Soc
Background The implantable cardioverter–defibrillator (ICD) is highly effective in reducing
mortality among patients at risk for fatal arrhythmias, but inappropriate ICD activations are …
mortality among patients at risk for fatal arrhythmias, but inappropriate ICD activations are …