A single-chain and fast-responding light-inducible Cre recombinase as a novel optogenetic switch
H Duplus-Bottin, M Spichty, G Triqueneaux, C Place… - Elife, 2021 - elifesciences.org
Optogenetics enables genome manipulations with high spatiotemporal resolution, opening
exciting possibilities for fundamental and applied biological research. Here, we report the …
exciting possibilities for fundamental and applied biological research. Here, we report the …
Genomics of cellular proliferation in periodic environmental fluctuations
…, M Richard, E Fulcrand, H Duplus‐Bottin… - Molecular Systems …, 2018 - embopress.org
Living systems control cell growth dynamically by processing information from their environment.
Although responses to a single environmental change have been intensively studied, …
Although responses to a single environmental change have been intensively studied, …
[HTML][HTML] Exploiting single-cell quantitative data to map genetic variants having probabilistic effects
Despite the recent progress in sequencing technologies, genome-wide association studies (GWAS)
remain limited by a statistical-power issue: many polymorphisms contribute little to …
remain limited by a statistical-power issue: many polymorphisms contribute little to …
A monogenic and fast-responding Light-Inducible Cre recombinase as a novel optogenetic switch
H Duplus-Bottin, M Spichty, G Triqueneaux, C Place… - bioRxiv, 2020 - biorxiv.org
Optogenetics enables genome manipulations with high spatiotemporal resolution, opening
exciting possibilities for fundamental and applied biological research. Here, we report the …
exciting possibilities for fundamental and applied biological research. Here, we report the …
Assigning function to natural allelic variation via dynamic modeling of gene network induction
M Richard, F Chuffart, H Duplus‐Bottin… - Molecular Systems …, 2018 - embopress.org
More and more natural DNA variants are being linked to physiological traits. Yet, understanding
what differences they make on molecular regulations remains challenging. Important …
what differences they make on molecular regulations remains challenging. Important …
Genomics of cellular proliferation under periodic stress
J Salignon, M Richard, E Fulcrand, G Yvert - bioRxiv, 2017 - biorxiv.org
… , Hélène Duplus-Bottin for technical help on strains constructions, David Stillman for plasmids,
Sandrine Mouradian and SFR Biosciences Gerland-Lyon Sud (UMS3444/US8) for access …
Sandrine Mouradian and SFR Biosciences Gerland-Lyon Sud (UMS3444/US8) for access …
Meeting report on experimental approaches to evolution and ecology using Yeast and other model systems
… Helen Murphy (College of William and Mary) presented a system to study the evolution of
biofilm formation and plastic adherence. In addition to developing a simple method (…
biofilm formation and plastic adherence. In addition to developing a simple method (…
[HTML][HTML] The promise of optogenetics for bioproduction: dynamic control strategies and scale-up instruments
Progress in metabolic engineering and synthetic and systems biology has made bioproduction
an increasingly attractive and competitive strategy for synthesizing biomolecules, …
an increasingly attractive and competitive strategy for synthesizing biomolecules, …
Genomics of fitness in periodic stress
J Salignon - 2017 - theses.hal.science
Organisms live in dynamic environments. However, most experimental approaches study the
function and selection of genes in steady environments. Therefore, natural selection acting …
function and selection of genes in steady environments. Therefore, natural selection acting …
Structure of a light-activated LOV protein dimer that regulates transcription
Light, oxygen, or voltage (LOV) protein domains are present in many signaling proteins in
bacteria, archaea, protists, plants, and fungi. The LOV protein VIVID (VVD) of the filamentous …
bacteria, archaea, protists, plants, and fungi. The LOV protein VIVID (VVD) of the filamentous …