H3K4 tri‐methylation provides an epigenetic signature of active enhancers
…, M Belhocine, F Koch, H Holota… - The EMBO …, 2011 - embopress.org
Combinations of post‐translational histone modifications shape the chromatin landscape
during cell development in eukaryotes. However, little is known about the modifications exactly …
during cell development in eukaryotes. However, little is known about the modifications exactly …
Bromodomain‐dependent stage‐specific male genome programming by Brdt
…, K Pernet, A Debernardi, F Lopez, H Holota… - The EMBO …, 2012 - embopress.org
Male germ cell differentiation is a highly regulated multistep process initiated by the commitment
of progenitor cells into meiosis and characterized by major chromatin reorganizations in …
of progenitor cells into meiosis and characterized by major chromatin reorganizations in …
Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B
…, M Jamshidikia, S Barral, H Holota… - Genes & …, 2013 - genesdev.cshlp.org
The conversion of male germ cell chromatin to a nucleoprotamine structure is fundamental
to the life cycle, yet the underlying molecular details remain obscure. Here we show that an …
to the life cycle, yet the underlying molecular details remain obscure. Here we show that an …
[HTML][HTML] Using metabarcoding to reveal and quantify plant-pollinator interactions
A Pornon, N Escaravage, M Burrus, H Holota… - Scientific reports, 2016 - nature.com
Given the ongoing decline of both pollinators and plants, it is crucial to implement effective
methods to describe complex pollination networks across time and space in a comprehensive …
methods to describe complex pollination networks across time and space in a comprehensive …
[HTML][HTML] Divergent transcription is associated with promoters of transcriptional regulators
Background Divergent transcription is a wide-spread phenomenon in mammals. For instance,
short bidirectional transcripts are a hallmark of active promoters, while longer transcripts …
short bidirectional transcripts are a hallmark of active promoters, while longer transcripts …
[HTML][HTML] Transcriptomics Reveal Several Gene Expression Patterns in the Piezophile Desulfovibrio hydrothermalis in Response to Hydrostatic Pressure
A Amrani, A Bergon, H Holota, C Tamburini, M Garel… - PloS one, 2014 - journals.plos.org
RNA-seq was used to study the response of Desulfovibrio hydrothermalis, isolated from a
deep-sea hydrothermal chimney on the East-Pacific Rise at a depth of 2,600 m, to various …
deep-sea hydrothermal chimney on the East-Pacific Rise at a depth of 2,600 m, to various …
[HTML][HTML] Nuclear receptor metabolism of bile acids and xenobiotics: a coordinated detoxification system with impact on health and diseases
…, L Thirouard, L Sedès, M Monrose, H Holota… - International journal of …, 2018 - mdpi.com
Structural and functional studies have provided numerous insights over the past years on
how members of the nuclear hormone receptor superfamily tightly regulate the expression of …
how members of the nuclear hormone receptor superfamily tightly regulate the expression of …
[PDF][PDF] CD8+ T cells from human neonates are biased toward an innate immune response
…, O Ramírez-Pliego, A Bergon, B Loriod, H Holota… - Cell reports, 2016 - cell.com
To better understand why human neonates show a poor response to intracellular pathogens,
we compared gene expression and histone modification profiles of neonatal naive CD8 + T …
we compared gene expression and histone modification profiles of neonatal naive CD8 + T …
[HTML][HTML] A positive feed-forward loop associating EGR1 and PDGFA promotes proliferation and self-renewal in glioblastoma stem cells
N Sakakini, L Turchi, A Bergon, H Holota… - Journal of Biological …, 2016 - ASBMB
Glioblastomas are the most common primary brain tumors, highly vascularized, infiltrating,
and resistant to current therapies. This cancer leads to a fatal outcome in less than 18 months. …
and resistant to current therapies. This cancer leads to a fatal outcome in less than 18 months. …
A novel locus on chromosome 1 underlies the evolution of a melanic plumage polymorphism in a wild songbird
…, C Mould, J Bruxaux, H Holota… - Royal Society …, 2017 - royalsocietypublishing.org
Understanding the mechanisms responsible for phenotypic diversification within and
among species ultimately rests with linking naturally occurring mutations to functionally and …
among species ultimately rests with linking naturally occurring mutations to functionally and …