User profiles for H. A. Thorpe

Harry A Thorpe

- Verified email at medisin.uio.no - Cited by 784

Hayley HA Thorpe

- Verified email at uwo.ca - Cited by 259

[HTML][HTML] A large-scale genomic snapshot of Klebsiella spp. isolates in Northern Italy reveals limited transmission between clinical and non-clinical settings

HA Thorpe, R Booton, T Kallonen, MJ Gibbon… - Nature …, 2022 - nature.com
The Klebsiella group, found in humans, livestock, plants, soil, water and wild animals, is
genetically and ecologically diverse. Many species are opportunistic pathogens and can …

PIRATE: A fast and scalable pangenomics toolbox for clustering diverged orthologues in bacteria

SC Bayliss, HA Thorpe, NM Coyle, SK Sheppard… - …, 2019 - academic.oup.com
… Harry A Thorpe , Harry A Thorpe … Sion C Bayliss, Harry A Thorpe, Nicola M Coyle, Samuel
K Sheppard, Edward J Feil, PIRATE: A fast and scalable pangenomics toolbox for clustering …

[HTML][HTML] Evolutionary Trade-Offs Underlie the Multi-faceted Virulence of Staphylococcus aureus

…, M Yokoyama, K Ouadi, E Feil, HA Thorpe… - PLoS …, 2015 - journals.plos.org
Bacterial virulence is a multifaceted trait where the interactions between pathogen and host
factors affect the severity and outcome of the infection. Toxin secretion is central to the …

The stealthy superbug: the role of asymptomatic enteric carriage in maintaining a long-term hospital outbreak of ST228 methicillin-resistant Staphylococcus aureus

…, AE Sheppard, DW Crook, R James, HA Thorpe… - MBio, 2016 - Am Soc Microbiol
… In contrast, our tertiary care hospital experienced a 4-year outbreak between 2008 and
2012 that affected over 1,600 patients and was due to the HA-MRSA sequence type 228 (ST228) …

[HTML][HTML] Strong pathogen competition in neonatal gut colonisation

T Mäklin, HA Thorpe, AK Pöntinen… - Nature …, 2022 - nature.com
Opportunistic bacterial pathogen species and their strains that colonise the human gut are
generally understood to compete against both each other and the commensal species …

Comparative analyses of selection operating on nontranslated intergenic regions of diverse bacterial species

HA Thorpe, SC Bayliss, LD Hurst, EJ Feil - Genetics, 2017 - academic.oup.com
… Harry A Thorpe , Harry A Thorpe … All of the code used in the analysis is available at
https://github.com/harry-thorpe/Intergenic_selection_paper under the GPLv3 license. The complete …

Piggy: a rapid, large-scale pan-genome analysis tool for intergenic regions in bacteria

HA Thorpe, SC Bayliss, SK Sheppard, EJ Feil - Gigascience, 2018 - academic.oup.com
… Harry A Thorpe , Harry A Thorpe … Harry A Thorpe, Sion C Bayliss, Samuel K Sheppard,
Edward J Feil, Piggy: a rapid, large-scale pan-genome analysis tool for intergenic regions in …

[HTML][HTML] Description of Klebsiella spallanzanii sp. nov. and of Klebsiella pasteurii sp. nov.

…, V Passet, M Corbella, HA Thorpe… - Frontiers in …, 2019 - frontiersin.org
Klebsiella oxytoca causes opportunistic human infections and post-antibiotic haemorrhagic
diarrhea. This Enterobacteriaceae species is genetically heterogeneous and is currently …

[HTML][HTML] Adolescent substance use and the brain: Behavioral, cognitive and neuroimaging correlates

S Hamidullah, HHA Thorpe, JA Frie… - Frontiers in Human …, 2020 - frontiersin.org
Adolescence is an important ontogenetic period that is characterized by behaviors such as
enhanced novelty-seeking, impulsivity, and reward preference, which can give rise to an …

[HTML][HTML] Whole genome sequencing and phylogenetic analysis of strains of the agent of Lyme disease Borrelia burgdorferi from Canadian emergence zones

…, G Margos, S Mechai, G Van Domselaar, HA Thorpe… - Scientific Reports, 2018 - nature.com
Lyme disease is emerging in southern Canada due to range expansion of the tick vector,
followed by invasion of the agent of Lyme disease Borrelia burgdorferi sensu stricto. Strain …