Extension of the interval between vaccine doses for the BNT162b2 mRNA vaccine was
introduced in the United Kingdom to accelerate population coverage with a single dose. At this …

MAIT cells are an unconventional T cell population that can be activated through both TCR-dependent
and TCR-independent mechanisms. Here, we examined the impact of …

The response to the coronavirus disease 2019 (COVID-19) pandemic has been hampered
by lack of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Interactions with commensal microbes shape host immunity on multiple levels and play a
pivotal role in human health and disease. Tissue-dwelling, antigen-specific T cells are poised …

Both infection and vaccination, alone or in combination, generate antibody and T cell
responses against SARS-CoV-2. However, the maintenance of such responses – and hence …

Obesity and type 2 diabetes (DM) are risk factors for severe COVID-19 outcomes, which
disproportionately affect South Asian populations. This study aims to investigate the humoral …

Mucosal-associated invariant T (MAIT) cells are an abundant innate-like T cell subset in
humans, enriched in mucosal tissues and the liver. MAIT cells express a semi-invariant T cell …

Introduction MAIT cells (Mucosa-Associated Invariant T cells) are highly enriched in the
human liver, representing about 20-50% of intrahepatic CD8+ T cells. These cells express …

Objective: Obesity and type 2 diabetes (DM) are risk factors for severe COVID-19 outcomes,
which disproportionately affect South Asian populations. This study aims to investigate the …

The response to the coronavirus disease 2019 (COVID-19) pandemic has been hampered
by lack of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …