Overexpression screens identify conserved dosage chromosome instability genes in yeast and human cancer
S Duffy, HK Fam, YK Wang, EB Styles… - Proceedings of the …, 2016 - National Acad Sciences
Somatic copy number amplification and gene overexpression are common features of many
cancers. To determine the role of gene overexpression on chromosome instability (CIN), we …
cancers. To determine the role of gene overexpression on chromosome instability (CIN), we …
Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression
…, K Beirnes, C Myung, D Leung, HK Fam… - Human molecular …, 2012 - academic.oup.com
Biallelic mutations of the DNA annealing helicase SMARCAL1 (SWI/SNF-related, matrix-associated,
actin-dependent regulator of chromatin, subfamily a-like 1) cause Schimke immuno-…
actin-dependent regulator of chromatin, subfamily a-like 1) cause Schimke immuno-…
Identification of a putative Tdp1 inhibitor (CD00509) by in vitro and cell-based assays
RA Dean, HK Fam, J An, K Choi… - Journal of …, 2014 - journals.sagepub.com
… Because Tdp1 is a member of the phospholipase D (PLD) family, known inhibitors of the
PLD family such as vanadate, paromomycin, lividomycin, and several teracyclines have been …
PLD family such as vanadate, paromomycin, lividomycin, and several teracyclines have been …
TDP1 and PARP1 deficiency are cytotoxic to rhabdomyosarcoma cells
HK Fam, C Walton, SA Mitra, M Chowdhury… - Molecular Cancer …, 2013 - AACR
Rhabdomyosarcoma is the most common soft tissue sarcoma in children. Metastatic
rhabdomyosarcoma in children has a 5-year event-free survival rate of <30%, and a recent clinical …
rhabdomyosarcoma in children has a 5-year event-free survival rate of <30%, and a recent clinical …
[HTML][HTML] Reactive oxygen species stress increases accumulation of tyrosyl-DNA phsosphodiesterase 1 within mitochondria
HK Fam, K Choi, L Fougner, CJ Lim, CF Boerkoel - Scientific reports, 2018 - nature.com
… Fam, HK et al. Expression profile and mitochondrial colocalization of Tdp1 in peripheral
human tissues. J Mol Histol 44, 481–494, https://doi.org/10.1007/s10735-013-9496-5 (2013). …
human tissues. J Mol Histol 44, 481–494, https://doi.org/10.1007/s10735-013-9496-5 (2013). …
Expression profile and mitochondrial colocalization of Tdp1 in peripheral human tissues
HK Fam, MK Chowdhury, C Walton, K Choi… - Journal of molecular …, 2013 - Springer
… The degree of Tdp1 expression in each individual was independently judged by HK Fam,
MK Chowdhury, C. Walton and G. Hendson and given a score ranging from no expression to …
MK Chowdhury, C. Walton and G. Hendson and given a score ranging from no expression to …
[HTML][HTML] Using information and communication technologies for family communication and its association with family well-being in Hong Kong: FAMILY project
… ) and 63.24% (822/1300) had monthly family income of HK $20,000 or greater (average
monthly income in Hong Kong was HK $20,200). Among 611 unemployed participants (40.66%, …
monthly income in Hong Kong was HK $20,200). Among 611 unemployed participants (40.66%, …
[HTML][HTML] Psychometric evaluation of the Chinese version of the Subjective Happiness Scale: evidence from the Hong Kong FAMILY Cohort
… Hong Kong and rapidly developing areas in mainland China and other Asian nations,
our Hong Kong … However, our sample was similar to the Hong Kong census population in …
our Hong Kong … However, our sample was similar to the Hong Kong census population in …
[BOOK][B] Working daughters of Hong Kong: Filial piety or power in the family?
JW Salaff - 1995 - books.google.com
… to the structural underpinnings of Hong Kong family lives. The two main practices of the
Chinese family that compel members to center their loyalty on the family and kinship units are …
Chinese family that compel members to center their loyalty on the family and kinship units are …
[HTML][HTML] Effects of depressive symptoms and family satisfaction on health related quality of life: the Hong Kong FAMILY study
… Data were obtained from the Hong Kong FAMILY Project baseline survey in 2009–2011,
which included 16,039 community residents (age ≥20). The FS was measured using the …
which included 16,039 community residents (age ≥20). The FS was measured using the …