The sequence of the human genome
…, X Lin, F Lu, GV Merkulov, N Milshina, HM Moore… - science, 2001 - science.org
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …
A review of preanalytical factors affecting molecular, protein, and morphological analysis of formalin-fixed, paraffin-embedded (FFPE) tissue: how well do you know …
…, SR Greytak, HM Moore - Archives of pathology …, 2014 - meridian.allenpress.com
Context Formalin fixation and paraffin embedding is a timeless, cost-efficient, and widely
adopted method of preserving human tissue biospecimens that has resulted in a substantial …
adopted method of preserving human tissue biospecimens that has resulted in a substantial …
Effects of preanalytical variables on the detection of proteins by immunohistochemistry in formalin-fixed, paraffin-embedded tissue
KB Engel, HM Moore - Archives of pathology & laboratory …, 2011 - meridian.allenpress.com
Context.—While formalin fixation and paraffin embedding has become a universal
mechanism of tissue preservation and a gold standard for immunohistochemistry, fixation and …
mechanism of tissue preservation and a gold standard for immunohistochemistry, fixation and …
The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans
…, R Little, S Koester, LJ Carithers, HM Moore… - Science, 2015 - science.org
Understanding the functional consequences of genetic variation, and how it affects complex
human disease and quantitative traits, remains a critical challenge for biomedicine. We …
human disease and quantitative traits, remains a critical challenge for biomedicine. We …
A novel approach to high-quality postmortem tissue procurement: the GTEx project
The Genotype-Tissue Expression (GTEx) project, sponsored by the NIH Common Fund,
was established to study the correlation between human genetic variation and tissue-specific …
was established to study the correlation between human genetic variation and tissue-specific …
[HTML][HTML] The genotype-tissue expression (GTEx) project
LJ Carithers, HM Moore - Biopreservation and biobanking, 2015 - ncbi.nlm.nih.gov
(NCI) and its partners in collecting high quality post-mortem biospecimens for a major
National Institutes of Health (NIH) research program, the Genotype-Tissue Expression (GTEx) …
National Institutes of Health (NIH) research program, the Genotype-Tissue Expression (GTEx) …
Biospecimen reporting for improved study quality (BRISQ)
HM Moore, AB Kelly, SD Jewell… - Journal of proteome …, 2011 - ACS Publications
Human biospecimens are subject to a number of different collection, processing, and storage
factors that can significantly alter their molecular composition and consistency. These …
factors that can significantly alter their molecular composition and consistency. These …
Effect of predicted protein-truncating genetic variants on the human transcriptome
…, R Little, S Koester, LJ Carithers, HM Moore… - Science, 2015 - science.org
Accurate prediction of the functional effect of genetic variation is critical for clinical genome
interpretation. We systematically characterized the transcriptome effects of protein-truncating …
interpretation. We systematically characterized the transcriptome effects of protein-truncating …
[PDF][PDF] A targeting modality for destruction of RNA polymerase I that possesses anticancer activity
…, L Colis, H Liu, R Trivedi, MS Moubarek, HM Moore… - Cancer cell, 2014 - cell.com
We define the activity and mechanisms of action of a small molecule lead compound for
cancer targeting. We show that the compound, BMH-21, has wide and potent antitumorigenic …
cancer targeting. We show that the compound, BMH-21, has wide and potent antitumorigenic …
Extracorporeal membrane oxygenation for adult respiratory failure
GJ Peek, HM Moore, N Moore, AW Sosnowski… - Chest, 1997 - Elsevier
Objectives To review the first 50 patients to receive extracorporeal membrane oxygenation (ECMO)
for respiratory failure at Glenfield Hospital, and to compare them with published …
for respiratory failure at Glenfield Hospital, and to compare them with published …