Dissecting cancer through mathematics: from the cell to the animal model
HM Byrne - Nature Reviews Cancer, 2010 - nature.com
… In recent work, Byrne and Drasdo 34 have developed complementary cell-based and
continuum models of MCS growth that exhibited similar growth kinetics. By fitting the profiles for the …
continuum models of MCS growth that exhibited similar growth kinetics. By fitting the profiles for the …
Antibodies and antibody-derived analytical biosensors
S Sharma, H Byrne, RJ O'Kennedy - Essays in biochemistry, 2016 - portlandpress.com
… Immobilization of the Ab on to the sensor surface through the antigen-binding sites,
encompassing the V H and C H regions, results in either decreased or entirely eliminated binding …
encompassing the V H and C H regions, results in either decreased or entirely eliminated binding …
Modelling aspects of cancer dynamics: a review
Cancer is a complex disease in which a variety of factors interact over a wide range of spatial
and temporal scales with huge datasets relating to the different scales available. However, …
and temporal scales with huge datasets relating to the different scales available. However, …
Reinforcement of hydrogels using three-dimensionally printed microfibres
…, EM Van Bussel, LS Kimpton, HM Byrne… - Nature …, 2015 - nature.com
… After etching, the scaffolds were washed in deionized H 2 O until the pH reached 7.4, and
then air-dried. The effect of etching was evaluated by measuring the fibre diameter (ImageJ) …
then air-dried. The effect of etching was evaluated by measuring the fibre diameter (ImageJ) …
In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells
…, A Casey, B Cottineau, G Chambers, HJ Byrne… - Toxicology in vitro, 2007 - Elsevier
… Cytotoxicity parameters evaluated in this study, following 24 h exposure to both materials
included the metabolic, lysosomal, and mitochondrial activities of the cells. In addition total …
included the metabolic, lysosomal, and mitochondrial activities of the cells. In addition total …
A cellular automaton model for tumour growth in inhomogeneous environment
… , Q ̇ ref , k m and k s are constants described below, H is the haematocrit, τ w =RΔP/L is the
… increases with decreasing red cell flux, Q ̇ H . The constant k m indicates how rapidly the …
… increases with decreasing red cell flux, Q ̇ H . The constant k m indicates how rapidly the …
Growth of nonnecrotic tumors in the presence and absence of inhibitors
HM Byrne, MAJ Chaplain - Mathematical biosciences, 1995 - Elsevier
In this article a model for the evolution of a spherically symmetric, nonnecrotic tumor is
presented. The effects of nutrients and inhibitors on the existence and stability of time-…
presented. The effects of nutrients and inhibitors on the existence and stability of time-…
Modelling solid tumour growth using the theory of mixtures
H Byrne, L Preziosi - … medicine and biology: a journal of the …, 2003 - ieeexplore.ieee.org
In this paper the theory of mixtures is used to develop a two‐phase model of an avascular
tumour, which comprises a solid, cellular, phase and a liquid phase. Mass and momentum …
tumour, which comprises a solid, cellular, phase and a liquid phase. Mass and momentum …
[PDF][PDF] A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
…, A Brown, J Broxholme, D Buck, KL Burnham, H Byrne… - Cell, 2022 - cell.com
… The MEgrey60 module was more highly expressed in critical COVID-19 than sepsis (Figure
S3H), … (H) Association of PCs of expression variance within minor cell subsets in COVID-19 …
S3H), … (H) Association of PCs of expression variance within minor cell subsets in COVID-19 …
Reverse saturable absorption in tetraphenylporphyrins
A decrease of the light transmission with increasing excitation intensity is observed in
tetraphenylporphyrin/toluene solutions irradiated with 80 ps pulses at λ=532 nm. The experimental …
tetraphenylporphyrin/toluene solutions irradiated with 80 ps pulses at λ=532 nm. The experimental …