Renewed discussion about whether or not adult neurogenesis exists in the human
hippocampus, and the nature and strength of the supporting evidence, has been reignited by two …

… the potential of neural precursors to remain in a quiescent Correspondence to: HA Cameron
… [3H]thymidine 1 h after injection, in the adult dentate gyrus are apparently nonimmunoreac- …

… a mean cell cycle length of 24.7 h and a dividing population of 9,400 … (Cameron and McKay,
2001). In young adult mice, the calculated cell cycle time is 13 h, of which S-phase lasts 6.5 h…

… h to four weeks following [ 3 H]thymidine administration. Light-microscopic examination revealed
a negligible number of [ 3 H… However, by two weeks after [ 3 H]thymidine administration, …

… By using this high dose of BrdU along with a second S-phase marker, [ 3 H]thymidine, we
found that young adult rats have 9,400 dividing cells proliferating with a cell cycle time of 25 …

… secondary antibodies (Vector labo~tories, diluted I : 50 in PBS with goat normal serum)
for 2 h. The sections were again rinsed in PBS and incubated for 2 h in avidinbiotin-horseradish …

Glucocorticoids are released in response to stressful experiences and serve many beneficial
homeostatic functions. However, dysregulation of glucocorticoids is associated with …

Using powder metallurgical techniques, cylindrical rods of a cast cobalt-base alloy (ASTM F-75)
were coated with cobalt-base alloy powder in 4 particle size ranges. The particles, …

… In order to test this hypothesis, we examined the numbers of newly born neurons using ‘H-thymidine
autoradiography and immunohistochemistry for the neuronal marker neuron-…

The production of hippocampal granule neurons continues throughout adulthood but
dramatically decreases in old age. Here we show that reducing corticosteroid levels in aged rats …