An expanded genome-wide association study of type 2 diabetes in Europeans

…, L Yengo, L Jiang, T Sparso, HA Kestler, H Chheda… - Diabetes, 2017 - Am Diabetes Assoc
To characterize type 2 diabetes (T2D)-associated variation across the allele frequency spectrum,
we conducted a meta-analysis of genome-wide association data from 26,676 T2D case …

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

…, M Frånberg, RJ Strawbridge, H Kestler, H Chheda… - Nature …, 2015 - nature.com
We performed fine mapping of 39 established type 2 diabetes (T2D) loci in 27,206 cases and
57,574 controls of European ancestry. We identified 49 distinct association signals at these …

[BOOK][B] Tropical grassland husbandry.

LV Crowder, HR Chheda - 1982 - cabdirect.org
This latest volume in the Tropical Agriculture Series is intended as a reference guide for
researchers, specialists and husbandrymen as well as students and teachers of tropical …

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

…, L Crooks, J McRae, J Suvisaari, H Chheda… - Nature …, 2016 - nature.com
By analyzing the whole-exome sequences of 4,264 schizophrenia cases, 9,343 controls
and 1,077 trios, we identified a genome-wide significant association between rare loss-of-…

Minimally invasive parathyroidectomy facilitated by intraoperative nuclear mapping

J Norman, H Chheda - Surgery, 1997 - Elsevier
Background. The inability to predict the location and number of diseased parathyroid glands
has precluded the wide acceptance of unilateral neck exploration for primary …

Minimally Invasive Parathyroidectomy for Primary Hyperparathyroidism: Decreasing Operative Time and Potential Complications while Improving Cosmetic Results …

J Norman, H Chheda, C Farrell… - The American …, 1998 - search.proquest.com
… Results were compared to the preceding 25 parathyroid explorations for primary HPT H
due to a single adenoma, which were nondirected and included bilateral neck exploration. All …

[PDF][PDF] Amazon review classification and sentiment analysis

A Bhatt, A Patel, H Chheda, K Gawande - International Journal of …, 2015 - Citeseer
Reviews on Amazon are not only related to the product but also the service given to the
customers. If users get clear bifurcation about product reviews and service reviews it will be …

[HTML][HTML] Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

…, V Bellón, V Boeva, K Bunte, H Chheda… - Nature …, 2016 - nature.com
… Despite a significant genetic heritability estimate of treatment non-response trait (h 2 =0.18,
P value=0.02), no significant genetic contribution to prediction accuracy is observed. Results …

[HTML][HTML] Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML

O Brück, S Blom, O Dufva, R Turkki, H Chheda… - Leukemia, 2018 - nature.com
Increasing evidence suggests that the immune system affects prognosis of chronic myeloid
leukemia (CML), but the detailed immunological composition of the leukemia bone marrow (…

[HTML][HTML] Whole-genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom

H Chheda, P Palta, M Pirinen, S McCarthy… - European Journal of …, 2017 - nature.com
Isolated populations with enrichment of variants due to recent population bottlenecks provide
a powerful resource for identifying disease-associated genetic variants and genes. As a …