User profiles for H. Galipeau
Heather J. GalipeauMcMaster University Verified email at mcmaster.ca Cited by 2859 |
Novel players in coeliac disease pathogenesis: role of the gut microbiota
… The FUT2 gene encodes an enzyme that controls the expression of the A, B, and h blood
group antigens in mucus and bodily secretions. In the intestinal mucosa, these antigens act as …
group antigens in mucus and bodily secretions. In the intestinal mucosa, these antigens act as …
[HTML][HTML] Celiac disease: a review of current concepts in pathogenesis, prevention, and novel therapies
JA Tye-Din, HJ Galipeau, D Agardh - Frontiers in pediatrics, 2018 - frontiersin.org
… Mechanisms underlying this association have not been elucidated and inconsistencies
across studies may relate to differences in techniques used to determine H. pylori status or H. …
across studies may relate to differences in techniques used to determine H. pylori status or H. …
The complex task of measuring intestinal permeability in basic and clinical science
HJ Galipeau, EF Verdu - Neurogastroenterology & Motility, 2016 - Wiley Online Library
… However, the viability of the tissue over the course of the experiment (usually 2 h) has been
questioned and removing the tissue from the host or utilizing cell lines may not reflect the …
questioned and removing the tissue from the host or utilizing cell lines may not reflect the …
Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host
… Plates were sealed with parafilm and incubated upside down and after 48 h (aerobic) or
120 h (anaerobic) the colony-forming units (CFUs) were quantified. Results are displayed as …
120 h (anaerobic) the colony-forming units (CFUs) were quantified. Results are displayed as …
Duodenal bacteria from patients with celiac disease and healthy subjects distinctly affect gluten breakdown and immunogenicity
Background & Aims Partially degraded gluten peptides from cereals trigger celiac disease (CD),
an autoimmune enteropathy occurring in genetically susceptible persons. Susceptibility …
an autoimmune enteropathy occurring in genetically susceptible persons. Susceptibility …
Novel fecal biomarkers that precede clinical diagnosis of ulcerative colitis
Background & Aims Altered gut microbiota composition and function have been associated
with inflammatory bowel diseases, including ulcerative colitis (UC), but the causality and …
with inflammatory bowel diseases, including ulcerative colitis (UC), but the causality and …
[HTML][HTML] Commensal microbiota induces colonic barrier structure and functions that contribute to homeostasis
CL Hayes, J Dong, HJ Galipeau, J Jury, J McCarville… - Scientific reports, 2018 - nature.com
The intestinal barrier encompasses structural, permeability and immune aspects of the gut
mucosa that, when disrupted, may contribute to chronic inflammation. Although gnotobiotic …
mucosa that, when disrupted, may contribute to chronic inflammation. Although gnotobiotic …
Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation
B Lamas, L Hernandez-Galan, HJ Galipeau… - Science translational …, 2020 - science.org
… (H) Shown is expression of genes in the AhR pathway in the proximal small intestine of
NOD/DQ8 mice fed a low-tryptophan (n = 6 to 7) or high-tryptophan (n = 5 to 7) diet. (I) Fecal …
NOD/DQ8 mice fed a low-tryptophan (n = 6 to 7) or high-tryptophan (n = 5 to 7) diet. (I) Fecal …
[HTML][HTML] Intestinal microbiota modulates gluten-induced immunopathology in humanized mice
HJ Galipeau, JL McCarville, S Huebener… - The American journal of …, 2015 - Elsevier
… in mouse cecum contents of clean SPF mice was evaluated every 2 weeks in cage
sentinels and at the end of the study in the experimental mice by PCR for Helicobacter bilis, H. …
sentinels and at the end of the study in the experimental mice by PCR for Helicobacter bilis, H. …
Differential induction of antimicrobial REGIII by the intestinal microbiota and Bifidobacterium breve NCC2950
…, CL Hayes, JP Motta, J Jury, HJ Galipeau… - Applied and …, 2013 - Am Soc Microbiol
… 1 h. Samples were stained overnight (4C) with rabbit anti-mouse REGIII-γ antibodies (1:100
dilution) (13) and for 1 h with secondary antibody at room temperature [goat anti-rabbit IgG(H…
dilution) (13) and for 1 h with secondary antibody at room temperature [goat anti-rabbit IgG(H…