User profiles for H. Galipeau

Heather J. Galipeau

McMaster University
Verified email at mcmaster.ca
Cited by 2859

Novel players in coeliac disease pathogenesis: role of the gut microbiota

EF Verdu, HJ Galipeau, B Jabri - Nature Reviews Gastroenterology & …, 2015 - nature.com
… The FUT2 gene encodes an enzyme that controls the expression of the A, B, and h blood
group antigens in mucus and bodily secretions. In the intestinal mucosa, these antigens act as …

[HTML][HTML] Celiac disease: a review of current concepts in pathogenesis, prevention, and novel therapies

JA Tye-Din, HJ Galipeau, D Agardh - Frontiers in pediatrics, 2018 - frontiersin.org
… Mechanisms underlying this association have not been elucidated and inconsistencies
across studies may relate to differences in techniques used to determine H. pylori status or H. …

The complex task of measuring intestinal permeability in basic and clinical science

HJ Galipeau, EF Verdu - Neurogastroenterology & Motility, 2016 - Wiley Online Library
… However, the viability of the tissue over the course of the experiment (usually 2 h) has been
questioned and removing the tissue from the host or utilizing cell lines may not reflect the …

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host

…, T Mayassi, JF Pierre, JD Ernest, HJ Galipeau… - Nature, 2018 - nature.com
… Plates were sealed with parafilm and incubated upside down and after 48 h (aerobic) or
120 h (anaerobic) the colony-forming units (CFUs) were quantified. Results are displayed as …

Duodenal bacteria from patients with celiac disease and healthy subjects distinctly affect gluten breakdown and immunogenicity

A Caminero, HJ Galipeau, JL McCarville, CW Johnston… - Gastroenterology, 2016 - Elsevier
Background & Aims Partially degraded gluten peptides from cereals trigger celiac disease (CD),
an autoimmune enteropathy occurring in genetically susceptible persons. Susceptibility …

Novel fecal biomarkers that precede clinical diagnosis of ulcerative colitis

HJ Galipeau, A Caminero, W Turpin, M Bermudez-Brito… - Gastroenterology, 2021 - Elsevier
Background & Aims Altered gut microbiota composition and function have been associated
with inflammatory bowel diseases, including ulcerative colitis (UC), but the causality and …

[HTML][HTML] Commensal microbiota induces colonic barrier structure and functions that contribute to homeostasis

CL Hayes, J Dong, HJ Galipeau, J Jury, J McCarville… - Scientific reports, 2018 - nature.com
The intestinal barrier encompasses structural, permeability and immune aspects of the gut
mucosa that, when disrupted, may contribute to chronic inflammation. Although gnotobiotic …

Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation

B Lamas, L Hernandez-Galan, HJ Galipeau… - Science translational …, 2020 - science.org
… (H) Shown is expression of genes in the AhR pathway in the proximal small intestine of
NOD/DQ8 mice fed a low-tryptophan (n = 6 to 7) or high-tryptophan (n = 5 to 7) diet. (I) Fecal …

[HTML][HTML] Intestinal microbiota modulates gluten-induced immunopathology in humanized mice

HJ Galipeau, JL McCarville, S Huebener… - The American journal of …, 2015 - Elsevier
… in mouse cecum contents of clean SPF mice was evaluated every 2 weeks in cage
sentinels and at the end of the study in the experimental mice by PCR for Helicobacter bilis, H. …

Differential induction of antimicrobial REGIII by the intestinal microbiota and Bifidobacterium breve NCC2950

…, CL Hayes, JP Motta, J Jury, HJ Galipeau… - Applied and …, 2013 - Am Soc Microbiol
… 1 h. Samples were stained overnight (4C) with rabbit anti-mouse REGIII-γ antibodies (1:100
dilution) (13) and for 1 h with secondary antibody at room temperature [goat anti-rabbit IgG(H