User profiles for H. Hoekstra

Henk Hoekstra

- Verified email at strw.leidenuniv.nl - Cited by 40385

Hopi Hoekstra

- Verified email at oeb.harvard.edu - Cited by 21142

The locus of evolution: evo devo and the genetics of adaptation

HE Hoekstra, JA Coyne - Evolution, 2007 - academic.oup.com
An important tenet of evolutionary developmental biology (“evo devo”) is that adaptive
mutations affecting morphology are more likely to occur in the cis-regulatory regions than in the …

[HTML][HTML] Cosmology and fundamental physics with the Euclid satellite

…, L Heisenberg, C Heymans, H Hoekstra… - Living reviews in …, 2018 - Springer
Euclid is a European Space Agency medium-class mission selected for launch in 2020 within
the cosmic vision 2015–2025 program. The main goal of Euclid is to understand the origin …

[HTML][HTML] Combining population genomics and quantitative genetics: finding the genes underlying ecologically important traits

JR Stinchcombe, HE Hoekstra - Heredity, 2008 - nature.com
A central challenge in evolutionary biology is to identify genes underlying ecologically important
traits and describe the fitness consequences of naturally occurring variation at these loci…

The Hubble Space Telescope cluster supernova survey. V. Improving the dark-energy constraints above z> 1 and building an early-type-hosted supernova sample

…, A Goobar, A Gude, T Hattori, H Hoekstra… - The Astrophysical …, 2012 - iopscience.iop.org
We present Advanced Camera for Surveys, NICMOS, and Keck adaptive-optics-assisted
photometry of 20 Type Ia supernovae (SNe Ia) from the Hubble Space Telescope (HST) Cluster …

[HTML][HTML] Double Digest RADseq: An Inexpensive Method for De Novo SNP Discovery and Genotyping in Model and Non-Model Species

…, JN Weber, EH Kay, HS Fisher, HE Hoekstra - PloS one, 2012 - journals.plos.org
The ability to efficiently and accurately determine genotypes is a keystone technology in
modern genetics, crucial to studies ranging from clinical diagnostics, to genotype-phenotype …

Euclid definition study report

…, P Gondoin, L Guzzo, J Hoar, H Hoekstra… - arXiv preprint arXiv …, 2011 - arxiv.org
Euclid is a space-based survey mission from the European Space Agency designed to
understand the origin of the Universe's accelerating expansion. It will use cosmological probes to …

The strength of phenotypic selection in natural populations

…, HE Hoekstra, JM Hoekstra… - The American …, 2001 - journals.uchicago.edu
… interesting result (HE Hoekstra, JM Hoekstra, D. Berrigan, SN Vignieri, A. Hoang, CE Hill,
P. … H. Hoekstra and colleagues (unpublished results) found that the average magnitude of …

[HTML][HTML] Sentinel-node biopsy or nodal observation in melanoma

…, OE Nieweg, DF Roses, HJ Hoekstra… - … England Journal of …, 2006 - Mass Medical Soc
Background We evaluated the contribution of sentinel-node biopsy to outcomes in patients
with newly diagnosed melanoma. Methods Patients with a primary cutaneous melanoma …

KiDS-450: cosmological parameter constraints from tomographic weak gravitational lensing

…, R Herbonnet, H Hoekstra… - Monthly Notices of …, 2017 - academic.oup.com
We present cosmological parameter constraints from a tomographic weak gravitational lensing
analysis of ∼450 deg 2 of imaging data from the Kilo Degree Survey (KiDS). For a flat Λ …

[HTML][HTML] Final trial report of sentinel-node biopsy versus nodal observation in melanoma

…, OE Nieweg, DF Roses, HJ Hoekstra… - … England Journal of …, 2014 - Mass Medical Soc
Background Sentinel-node biopsy, a minimally invasive procedure for regional melanoma
staging, was evaluated in a phase 3 trial. Methods We evaluated outcomes in 2001 patients …