User profiles for H. Kovar

Heinrich Kovar

Verified email at ccri.at
Cited by 13567

[PDF][PDF] Ewing sarcoma: current management and future approaches through collaboration

…, IJ Lewis, S Ferrari, MC Le Deley, H Kovar… - J Clin …, 2015 - researchgate.net
Ewing sarcoma (ES) is an aggressive sarcoma of bone and soft tissue occurring at any age
with a peak incidence in adolescents and young adults. The treatment of ES relies on a …

Ewing sarcoma

…, D Surdez, EM Tomazou, E de Álava, H Kovar… - Nature reviews Disease …, 2018 - nature.com
Ewing sarcoma is the second most frequent bone tumour of childhood and adolescence that
can also arise in soft tissue. Ewing sarcoma is a highly aggressive cancer, with a survival of …

Ewing's sarcoma family of tumors: current management

M Bernstein, H Kovar, M Paulussen, RL Randall… - The …, 2006 - academic.oup.com
… Heinrich Kovar , Heinrich Kovar … Mark Bernstein, Heinrich Kovar, Michael Paulussen, R.
Lor Randall, Andreas Schuck, Lisa A. Teot, Herbert Juergensg, Ewing's Sarcoma Family of …

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

…, B Plougastel, C Desmaze, T Melot, M Peter, H Kovar… - Nature, 1992 - nature.com
… Goubin, unpublished data), from a Ewing's sarcoma cell line (H. Kovar, unpublished data)
and from fetal brain (Stratagene catalogue number 937201). The 2390 bp EWS cDNA …

MIC2 is a specific marker for Ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of Ewing's sarcoma and …

IM Ambros, PF Ambros, S Strehl, H Kovar, H Gadner… - Cancer, 1991 - Wiley Online Library
This study reports on the specific expression of the MIC2 gene, a pseudoautosomal gene
located on the short arms of the X and Y chromosomes, on Ewing's sarcoma (ES) and …

EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation

…, L Quintanilla-Martinez, H Kovar… - Proceedings of the …, 2009 - National Acad Sciences
… for 24 h, collected, and then analyzed; siRNA transfectants were harvested after 48 h.
Each … (B) Real-time RT-PCR of different neuroectodermal and endothelial genes 60 h after …

Does expression of different EWS chimeric transcripts define clinically distinct risk groups of Ewing tumor patients?

…, TL Smith, H Jürgens, H Gadner, H Kovar - Journal of clinical …, 1996 - ascopubs.org
PURPOSE Because of the high heterogeneity of EWS gene fusions with FLI1 and ERG
genes due to variable chromosomal breakpoint locations in Ewing tumors (ET) (14 different …

Impact of EWS-ETS Fusion Type on Disease Progression in Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor: Prospective Results From the …

…, IJ Lewis, AW Craft, H Jürgens, H Kovar - Journal of Clinical …, 2010 - ascopubs.org
Purpose EWS-ETS fusion genes are the driving force in Ewing's sarcoma pathogenesis.
Because of the variable breakpoint locations in the involved genes, there is heterogeneity in …

[HTML][HTML] Ewing sarcoma—diagnosis, treatment, clinical challenges and future perspectives

…, SG DuBois, J Hardes, W Hartmann, H Kovar… - Journal of clinical …, 2021 - mdpi.com
Ewing sarcoma, a highly aggressive bone and soft-tissue cancer, is considered a prime
example of the paradigms of a translocation-positive sarcoma: a genetically rather simple …

Overexpression of the pseudoautosomal gene MIC2 in Ewing's sarcoma and peripheral primitive neuroectodermal tumor.

H Kovar, M Dworzak, S Strehl, E Schnell, IM Ambros… - Oncogene, 1990 - europepmc.org
Ewing's Sarcoma (ES), the second most frequent bone tumor in childhood and adolescence,
and the probably closely related peripheral primitive neuroectodermal tumor (pPNET) …