… Patient 1: A 77-year-old woman with abrupt onset of paresthesias in legs and hands that
progressed in 36 h to areflexic tetraplegia without bulbar signs. Seven days earlier she had …

… Only early H/M ratio data was evaluated in the present meta-… of the early H/M ratio were
similar to those of the delayed H/M … of the delayed H/M ratio was higher than that of the early H/M …

In the last few years, a lot of publications suggested that disabling cerebellar ataxias may
develop through immune-mediated mechanisms. In this consensus paper, we discuss the …

To learn about the carboxy-terminal extent of amyloid g-protein (Ag) composition of senile
plaques (SPs) in the brain affected with Alzheimer’s disease (AD), we employed two end-…

DECi-hertz Interferometer Gravitational wave Observatory (DECIGO) is the future Japanese
space gravitational wave antenna. It aims at detecting various kinds of gravitational waves …

… Unexpectedly, we observed positive PrP Sc -dependent ThT fluorescence within 24 h, both
… resulted in no increase in ThT fluorescence over 24 h; however, de novo formation of rPrP-…

… Accessible iron can react with H 2 O 2 produced during oxidative deamination of dopamine
… We showed that neuronal cell death induced by H 2 O 2 was enhanced by down regulation …

… H/M ratio in Parkinson’s disease was significantly lower than that in controls and the other
diseases. The H… In almost half of the patients in Hoehn and Yahr stage I, the H/M ratio was …

More than 100,000 genetic variants are reported to cause Mendelian disease in humans,
but the penetrance—the probability that a carrier of the purported disease-causing genotype …

RNA interference is a powerful tool for target-specific knockdown of gene expression.
However, efficient and safe in vivo delivery of short interfering RNA (siRNA) to the target organ, …