Evolutionarily conserved signaling pathways are essential for early embryogenesis, and
reducing or abolishing their activity leads to characteristic developmental defects. Classification …

An early step in intracellular transport is the selective recognition of a vesicle by its appropriate
target membrane, a process regulated by Rab GTPases via the recruitment of tethering …

… To meet this challenge, Morales-Navarrete et al. extended the free … Morales-Navarrete et al.
used the software to analyse liver … Morales-Navarrete et al.’s approach can rapidly generate …

Bile, the central metabolic product of the liver, is transported by the bile canaliculi network.
The impairment of bile flow in cholestatic liver diseases has urged a demand for insights into …

… h,i, Percentage of the cell volume occupied by LD: distribution (h) and statistics along the
CV–PV axis and overall (i). Hepatocytes with percentage of LD volume lower than 0.001% are …

… Copyright Morales-Navarrete et al. This article is distributed under the terms of the Creative
Commons Attribution License, which permits unrestricted use and redistribution provided that …

The mechanisms of organ size control remain poorly understood. A key question is how
cells collectively sense the overall status of a tissue. We addressed this problem focusing on …

Plasticity is an essential condition for cancer cells to invade surrounding tissues. The
nucleus is the most rigid cellular organelle and it undergoes substantial deformations to get …

During animal development, embryos undergo complex morphological changes over time.
Differences in developmental tempo between species are emerging as principal drivers of …

Lumen morphogenesis results from the interplay between molecular pathways and mechanical
forces. In several organs, epithelial cells share their apical surfaces to form a tubular …