Ficus spp.(fig): Ethnobotany and potential as anticancer and anti-inflammatory agents

EP Lansky, HM Paavilainen, AD Pawlus… - Journal of …, 2008 - Elsevier
This review explores medieval, ancient and modern sources for ethnopharmacological uses
of Ficus (fig) species, specifically for employment against malignant disease and …

Novel activities of safe-in-human broad-spectrum antiviral agents

…, H Lysvand, M Teppor, L Kakkola, H Paavilainen… - Antiviral research, 2018 - Elsevier
… The cells were grown for 24 h in cell growth medium. The media was replaced with virus
growth medium (VGM) containing 0.2% BSA, 2 mM l-glutamine, 0.35% NaHCO3, and 1 μg/mL L…

[HTML][HTML] Evaluating medicinal plants for anticancer activity

…, M Lichtenstein, S Sallon, H Paavilainen… - The Scientific World …, 2014 - hindawi.com
… From left to right: DNA extracted from control Colo205 cells, not exposed to any inducer (48
h; line 1); DNA extracted from cells exposed to extract 5 for 24 h (line 3), 48 h (line 5), 72 h (…

[BOOK][B] Figs: the genus Ficus

EP Lansky, HM Paavilainen - 2010 - taylorfrancis.com
With a history as ancient as any cultivated fruit, many believe the fig has been with us even
longer than the pomegranate. The Ficus constitutes one of the largest and hardiest genera of …

[HTML][HTML] Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection

…, I Julkunen, H Kallio-Kokko, H Paavilainen… - Journal of Biological …, 2012 - ASBMB
… Typically, 40,000 RPE cells or 600,000 PBMCs were seeded per well and grown for 24 h
or 7 days, respectively, in appropriate cell growth media. RPE cells and PBMC-derived …

[HTML][HTML] Using digital twin technology in engineering education–course concept to explore benefits and barriers

A Liljaniemi, H Paavilainen - Open Engineering, 2020 - degruyter.com
Digital Twin (DT) technology is an essential technology related to the Industry 4.0. In engineering
education, it is important that the curricula are kept up-to-date. By adopting new digital …

[HTML][HTML] Personalized cancer vaccine platform for clinically relevant oncolytic enveloped viruses

…, L Ylösmäki, A Louna, S Feola, H Paavilainen… - Molecular Therapy, 2018 - cell.com
The approval of the first oncolytic virus for the treatment of metastatic melanoma and the
compiling evidence that the use of oncolytic viruses can enhance cancer immunotherapies …

[HTML][HTML] Antiviral properties of chemical inhibitors of cellular anti-apoptotic Bcl-2 proteins

…, A Bugai, Y Akimov, S Kuivanen, H Paavilainen… - Viruses, 2017 - mdpi.com
… already at 12 h post infection, whereas no toxicity was detected for at least 36 h at 0.4 µM …
or ABT-263-treated mock-infected RPE cells at 12 h post infection (Figure S4). These results …

[HTML][HTML] Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice

…, A Nagaraj, T Öhman, S Kuivanen, H Paavilainen… - Cell Death & …, 2013 - nature.com
… assay 11 h after infection… h after infection. (d) Macrophages were non- or ABT-263-treated
(0.4 μM) and mock- or IAV-infected (WSN, moi 0.1), and virus production was determined 24 h

Regulation of kynurenine biosynthesis during influenza virus infection

…, X Saelens, I Julkunen, H Paavilainen… - The FEBS …, 2017 - Wiley Online Library
Influenza A viruses ( IAV s) remain serious threats to public health because of the shortage
of effective means of control. Developing more effective virus control modalities requires …