Non-alcoholic fatty liver disease (NAFLD) is a frequent accompaniment of obesity and insulin
resistance. With the prevalence approaching 85% in obese populations, new therapeutic …

The genus Castor comprises two species: the Eurasian beaver Castor fiber, and the North
American beaver Castor canadensis. Both species suffered from overexploitation, but have …

Over the past decade workplace and executive coaching has grown from a relatively novel
intervention to a mainstream developmental activity in organizations worldwide. The annual …

Over 225,000 independent Agrobacterium transferred DNA (T-DNA) insertion events in the
genome of the reference plant Arabidopsis thaliana have been created that represent near …

Heterogeneity and latent variables are now widely recognized as major sources of bias and
variability in high-throughput experiments. The most well-known source of latent variation in …

Here we report a high-quality draft genome sequence of the domestic dog (Canis familiaris),
together with a dense map of single nucleotide polymorphisms (SNPs) across breeds. The …

… Three- to four-month-old ffar2 −/− , ffar3 −/− , and wild-type littermate control 129/SvEv mice
were fasted for 4 h and then dosed with 0.75 units/kg insulin ip (Actrapid insulin, supplied by …

Rhinoviruses are the major cause of asthma exacerbations, and asthmatics have increased
susceptibility to rhinovirus and risk of invasive bacterial infections. Here we show deficient …

This book provides a full account of the North West Longitudinal Study of adolescent drug
use. This quantitative and qualitative research was the largest single survey of adolescent …

We used molecular markers to study genetic relationships in a diverse collection of 85
domestic dog breeds. Differences among breeds accounted for ∼30% of genetic variation. …