[HTML][HTML] The double-edged roles of ROS in cancer prevention and therapy

…, H Qi, Y Liu, C Duan, X Liu, T Xia, D Chen, H Piao… - Theranostics, 2021 - ncbi.nlm.nih.gov
… Unlike PRXs and GPXs, CAT converts H 2 O 2 to H 2 O without the participation of any … the
H 2 O 2 concentration. At high H 2 O 2 levels, CAT exhibits catalytic activity by converting H 2 …

[HTML][HTML] ROS-triggered endothelial cell death mechanisms: Focus on pyroptosis, parthanatos, and ferroptosis

D Zheng, J Liu, H Piao, Z Zhu, R Wei, K Liu - Frontiers in Immunology, 2022 - frontiersin.org
… This may be related to the generation of H 2 O 2 by NOX4. H 2 O 2 is considered an …
Furthermore, unlike superoxide, H 2 O 2 does not react appreciably with NO, and thus does …

[HTML][HTML] The role of exosomes and exosomal microRNA in cardiovascular disease

D Zheng, M Huo, B Li, W Wang, H Piao… - Frontiers in cell and …, 2021 - frontiersin.org
… /R model, which indicates that these exosomes exert a protective effect against myocardial
cell injury caused by H/R. In addition, exosomal miR-486-5p derived from BMSCs can repair …

[HTML][HTML] Activation of glucosidase via stress-induced polymerization rapidly increases active pools of abscisic acid

KH Lee, HL Piao, HY Kim, SM Choi, F Jiang… - Cell, 2006 - cell.com
… inhibitor of N-glycosylation, and treated with endo H or PNGase F. AtBG1:HA from tunicamycin…
Furthermore, the glycan moiety of AtBG1:HA is sensitive to both endo H and PNGase F, as …

[HTML][HTML] Low-dose metformin targets the lysosomal AMPK pathway through PEN2

…, M Zhang, Y Bao, W Jia, SY Lin, Z Ye, HL Piao… - Nature, 2022 - nature.com
… and 200 μM metformin for 2 h and 12 h, respectively, followed by … h, PEN2-2A does not
mediate AMPK activation by metformin. … with 200 μM metformin for 12 h, followed by analysis of p-…

Long noncoding RNA MALAT1 suppresses breast cancer metastasis

J Kim, HL Piao, BJ Kim, F Yao, Z Han, Y Wang, Z Xiao… - Nature …, 2018 - nature.com
MALAT1 has previously been described as a metastasis-promoting long noncoding RNA (lncRNA).
We show here, however, that targeted inactivation of the Malat1 gene in a transgenic …

Fructose-1, 6-bisphosphate and aldolase mediate glucose sensing by AMPK

…, M Zhu, YQ Wu, TY Li, Z Ye, SY Lin, H Yin, HL Piao… - Nature, 2017 - nature.com
… We also observed no changes in adenine nucleotide ratios in livers of mice starved for 16
h, … by a much larger activation for up to 2 h, while only the initial activation was observed if …

Preparation of stable nitrendipine nanosuspensions using the precipitation–ultrasonication method for enhancement of dissolution and oral bioavailability

D Xia, P Quan, H Piao, H Piao, S Sun, Y Yin… - European Journal of …, 2010 - Elsevier
The aim of this study was to prepare and characterize nitrendipine nanosuspensions to
enhance the dissolution rate and oral bioavailability of this drug. Nanosuspensions were …

A comprehensive analysis of PAX8 expression in human epithelial tumors

AR Laury, R Perets, H Piao, JF Krane… - The American journal …, 2011 - journals.lww.com
… G and H, A type B3 thymoma is strongly and diffusely positive for PAX8. I and J, In the rare
multinodular thymoma, neoplastic thymic epithelial cells are positive for PAX8 to a lesser …

[HTML][HTML] RBMS1 regulates lung cancer ferroptosis through translational control of SLC7A11

…, D Chen, S Fan, H Chen, HL Piao… - The Journal of …, 2021 - Am Soc Clin Investig
… (G and H) Bar graphs showing viability (G) and death (H) of H1299 cells with RBMS1
knockdown, with or without SLC7A11 reexpression and treated with erastin or erastin and Ferr-1. …