User profiles for H. Tsai

Hsinhan Tsai

- Verified email at berkeley.edu - Cited by 17068

Hui-Lien Tsai

- Verified email at mail.ncku.edu.tw - Cited by 7088

Hsing-Chen Tsai

- Verified email at Pfizer.Com - Cited by 4476

[HTML][HTML] Development of therapeutic antibodies for the treatment of diseases

RM Lu, YC Hwang, IJ Liu, CC Lee, HZ Tsai… - Journal of biomedical …, 2020 - Springer
… C H : domains of the constant region of the heavy chain; C L : constant domain of the light
chain; Fab and Fc: fragments resulting from proteolysis; V H : variable domain of the heavy …

[HTML][HTML] Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance

H Easwaran, HC Tsai, SB Baylin - Molecular cell, 2014 - cell.com
The existence of subpopulations of cells in cancers with increased tumor-initiating capacities
and self-renewal potential, often termed "cancer stem cells," is a much discussed and key …

Astrocytes and disease: a neurodevelopmental perspective

AV Molofsky, R Krenick, E Ullian, H Tsai… - Genes & …, 2012 - genesdev.cshlp.org
Astrocytes are no longer seen as a homogenous population of cells. In fact, recent studies
indicate that astrocytes are morphologically and functionally diverse and play critical roles in …

High-efficiency solution-processed perovskite solar cells with millimeter-scale grains

W Nie, H Tsai, R Asadpour, JC Blancon, AJ Neukirch… - Science, 2015 - science.org
State-of-the-art photovoltaics use high-purity, large-area, wafer-scale single-crystalline
semiconductors grown by sophisticated, high-temperature crystal growth processes. We …

Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura

…, EE Bouhassira, JD Upshaw Jr, D Ginsburg, HM Tsai - Nature, 2001 - nature.com
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening systemic illness of abrupt
onset and unknown cause. Proteolysis of the blood-clotting protein von Willebrand factor (VWF…

High-efficiency two-dimensional Ruddlesden–Popper perovskite solar cells

H Tsai, W Nie, JC Blancon, CC Stoumpos, R Asadpour… - Nature, 2016 - nature.com
… From the light stress tests for the 3D perovskites, we conclude that the observed degradation
in the first 10 h in the encapsulated and unencapsulated devices is similar, and so is …

High-spin molecules:[Mn12O12 (O2CR) 16 (H2O) 4]

R Sessoli, HL Tsai, AR Schake, S Wang… - Journal of the …, 1993 - ACS Publications
… The mixture was stirred for 4 h and filtered to remove a small amount of undissolved solid.
Hexanes (100 mL) were added to the filtrate, and the solution was stored overnight at room …

[HTML][HTML] Antibodies to von Willebrand factor–cleaving protease in acute thrombotic thrombocytopenic purpura

HM Tsai, ECY Lian - New England Journal of Medicine, 1998 - Mass Medical Soc
Background Thrombotic thrombocytopenic purpura is a potentially fatal disease characterized
by widespread platelet thrombi in the microcirculation. In the normal circulation, von …

Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning

HC Tsai, F Zhang, A Adamantidis, GD Stuber, A Bonci… - Science, 2009 - science.org
Natural rewards and drugs of abuse can alter dopamine signaling, and ventral tegmental
area (VTA) dopaminergic neurons are known to fire action potentials tonically or phasically …

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

…, B Juarez, SM Ku, JW Koo, D Ferguson, HC Tsai… - Nature, 2013 - nature.com
… Given the striking impairment in sucrose preference approximately 12 h after the optogenetic
activation of VTA neurons, we proposed that such stimulation might induce lasting changes …