Ketamine's rapid antidepressant effects are mediated by Ca2+-permeable AMPA receptors
…, MH Wustrau, IG Schmidt, H Mendez-Vazquez… - Elife, 2023 - elifesciences.org
Ketamine is shown to enhance excitatory synaptic drive in multiple brain areas, which is
presumed to underlie its rapid antidepressant effects. Moreover, ketamine’s therapeutic actions …
presumed to underlie its rapid antidepressant effects. Moreover, ketamine’s therapeutic actions …
The autism-associated loss of δ-catenin functions disrupts social behavior
H Mendez-Vazquez, RL Roach, K Nip… - Proceedings of the …, 2023 - National Acad Sciences
δ-catenin is expressed in excitatory synapses and functions as an anchor for the glutamatergic
AMPA receptor (AMPAR) GluA2 subunit in the postsynaptic density. The glycine 34 to …
AMPA receptor (AMPAR) GluA2 subunit in the postsynaptic density. The glycine 34 to …
Prenatal exposure to valproic acid reduces synaptic δ-catenin levels and disrupts ultrasonic vocalization in neonates
SH Roh, H Mendez-Vazquez, MF Sathler… - …, 2024 - Elsevier
Valproic acid (VPA) is an effective and commonly prescribed drug for epilepsy and bipolar
disorder. However, children born from mothers treated with VPA during pregnancy exhibit an …
disorder. However, children born from mothers treated with VPA during pregnancy exhibit an …
Ketamine's rapid antidepressant effects are mediated by Ca2+-permeable AMPA receptors in the hippocampus
…, MH Wustrau, IG Schmidt, H Mendez-Vazquez… - bioRxiv, 2022 - biorxiv.org
Ketamine is shown to enhance excitatory synaptic drive in the hippocampus, which is presumed
to underlie its rapid antidepressant effects. Moreover, ketamine’s therapeutic actions are …
to underlie its rapid antidepressant effects. Moreover, ketamine’s therapeutic actions are …