Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer disease

…, Y Chen, HH Kitzler, R Hammond, H Vogel… - Neurobiology of …, 2015 - Elsevier
Although amyloid plaques and neurofibrillary pathology play important roles in Alzheimer
disease (AD), our understanding of AD is incomplete, and the contribution of microglia and …

Profiling individual clinical responses by high-frequency serum neurofilament assessment in MS

…, U Proschmann, HH Kitzler, H Reichmann… - Neurology …, 2019 - AAN Enterprises
Objective To evaluate individual neurofilament light chain (NfL) variation over the time of
disease course and the potential of NfL measurement to predict treatment response in patients …

[HTML][HTML] Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers

…, M Keřkovský, A Khatibi, JW Kim, N Kinany, HH Kitzler… - Scientific Data, 2021 - nature.com
In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative
MRI protocol that provides valuable metrics for assessing spinal cord macrostructural and …

[HTML][HTML] Harnessing real-world data to inform decision-making: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS)

…, I Izbudak, SE Jones, BC Kieseier, HH Kitzler… - Frontiers in …, 2020 - frontiersin.org
… Kieseier 3 Hagen H. Kitzler Hagen H. Kitzler 7 Lauren Krupp Lauren Krupp 8 Yvonne W.
Lui Yvonne W. Lui 8 Xavier Montalban Xavier Montalban 9 Robert T. …

Deficient MWF mapping in multiple sclerosis using 3D whole-brain multi-component relaxation MRI

HH Kitzler, J Su, M Zeineh, C Harper-Little, A Leung… - Neuroimage, 2012 - Elsevier
Recent multiple sclerosis (MS) MRI research has highlighted the need to move beyond the
lesion-centric view and to develop and validate new MR imaging strategies that quantify the …

Multiple sclerosis lesion activity segmentation with attention-guided two-path CNNs

…, R Opfer, AC Ostwaldt, P Manogaran, HH Kitzler… - … Medical Imaging and …, 2020 - Elsevier
Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized
by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is …

[HTML][HTML] Automatic segmentation of the thalamus using a massively trained 3D convolutional neural network: higher sensitivity for the detection of reduced thalamus …

R Opfer, J Krüger, L Spies, AC Ostwaldt, HH Kitzler… - European …, 2023 - Springer
Objectives To develop an automatic method for accurate and robust thalamus segmentation
in T1w-MRI for widespread clinical use without the need for strict harmonization of …

[HTML][HTML] Fully automated longitudinal segmentation of new or enlarged multiple sclerosis lesions using 3D convolutional neural networks

…, N Gessert, AC Ostwaldt, P Manogaran, HH Kitzler… - NeuroImage: Clinical, 2020 - Elsevier
The quantification of new or enlarged lesions from follow-up MRI scans is an important
surrogate of clinical disease activity in patients with multiple sclerosis (MS). Not only is manual …

FDG PET/MR for lymph node staging in head and neck cancer

…, M Schneider, V Gudziol, HH Kitzler… - European Journal of …, 2014 - Elsevier
Objective To assess the diagnostic value of PET/MR (positron emission tomography/magnetic
resonance imaging) with FDG (18F-fluorodeoxyglucose) for lymph node staging in head …

Comparison of probabilistic and deterministic fiber tracking of cranial nerves

…, B Rieger, TA Juratli, G Schackert, HH Kitzler - Journal of …, 2016 - thejns.org
OBJECTIVE The depiction of cranial nerves (CNs) using diffusion tensor imaging (DTI) is of
great interest in skull base tumor surgery and DTI used with deterministic tracking methods …