[HTML][HTML] The genomic basis of adaptive evolution in threespine sticklebacks

…, BR Summers, AK Knecht, SD Brady, H Zhang… - Nature, 2012 - nature.com
Marine stickleback fish have colonized and adapted to thousands of streams and lakes
formed since the last ice age, providing an exceptional opportunity to characterize genomic …

[HTML][HTML] Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs

…, AR Sedaghat, MA McMahon, M Callender, H Zhang… - Nature medicine, 2008 - nature.com
Highly active antiretroviral therapy (HAART) can control HIV-1 replication 1 , 2 , but suboptimal
treatment allows for the evolution of resistance and rebound viremia 3 , 4 , 5 , 6 , 7 , 8 . A …

Kinetics of Human Immunodeficiency Virus Type 1 Decay following Entry into Resting CD4+ T Cells

Y Zhou, H Zhang, JD Siliciano, RF Siliciano - Journal of virology, 2005 - Am Soc Microbiol
In untreated human immunodeficiency virus type 1 (HIV-1) infection, most viral genomes in
resting CD4 + T cells are not integrated into host chromosomes. This unintegrated virus …

Novel single-cell-level phenotypic assay for residual drug susceptibility and reduced replication capacity of drug-resistant human immunodeficiency virus type 1

H Zhang, Y Zhou, C Alcock, T Kiefer, D Monie… - Journal of …, 2004 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1)-infected individuals who develop drug-resistant
virus during antiretroviral therapy may derive benefit from continued treatment for two …

Affinity maturation in trout: clonal dominance of high affinity antibodies late in the immune response

SL Kaattari, HL Zhang, W Khor, IM Kaattari… - Developmental & …, 2002 - Elsevier
The ability of an animal to develop a highly specific antibody response through affinity
maturation has been considered an integral part of the adaptive immune response. However, …

Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS

…, L You, J Wu, M Zhao, R Guo, H Zhang… - Journal of Leucocyte …, 2020 - academic.oup.com
Berberine (BBR) is an isoquinoline alkaloid extracted from several commonly used Chinese
herbs. Our previous studies demonstrated BBR-mediated alleviation of lung injury due to …

[HTML][HTML] Big data, big data analytics capability, and sustainable innovation performance

S Hao, H Zhang, M Song - Sustainability, 2019 - mdpi.com
Literature suggests that big data is a new competitive advantage and that it enhance
organizational performance. Yet, previous empirical research has provided conflicting results. …

[HTML][HTML] Fialuridine induces acute liver failure in chimeric TK-NOG mice: a model for detecting hepatic drug toxicity prior to human testing

D Xu, T Nishimura, S Nishimura, H Zhang… - PLoS …, 2014 - journals.plos.org
Background Seven of 15 clinical trial participants treated with a nucleoside analogue (fialuridine
[FIAU]) developed acute liver failure. Five treated participants died, and two required a …

Algal biorefinery to value-added products by using combined processes based on thermochemical conversion: a review

L Fan, H Zhang, J Li, Y Wang, L Leng, J Li, Y Yao, Q Lu… - Algal research, 2020 - Elsevier
Thermochemical processes, including gasification, liquefaction, and pyrolysis, are promising
technologies for algal conversion. Gasification is effective to convert algal biomass into fuel …

The Rubisco Small Subunit Is Involved in Tobamovirus Movement and Tm-22-Mediated Extreme Resistance

J Zhao, Q Liu, H Zhang, Q Jia, Y Hong, Y Liu - Plant Physiology, 2013 - academic.oup.com
The multifunctional movement protein ( MP ) of Tomato mosaic tobamovirus ( ToMV ) is
involved in viral cell-to-cell movement, symptom development, and resistance gene recognition. …