There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection.
We investigated the proteomic profile of extracellular vesicles and particles (EVPs) in …

The heterogeneity of exosomal populations has hindered our understanding of their biogenesis,
molecular composition, biodistribution and functions. By employing asymmetric flow field…

Tumor-secreted extracellular vesicles (EVs) are critical mediators of intercellular
communication between tumor cells and stromal cells in local and distant microenvironments. …

The development of effective therapies against brain metastasis is currently hindered by
limitations in our understanding of the molecular mechanisms driving it. Here we define the …

Background Immunotherapy with immune checkpoint inhibitors combined with an anti-angiogenic
tyrosine-kinase inhibitor (TKI) has been shown to improve overall survival versus anti-…

In recent years, 2-dimensional (2D) materials such as graphene and h-BN have been
spotlighted, because of their unique properties and high potential applicability. Among these 2D …

Recently, piezoelectricity has been observed in 2D atomically thin materials, such as
hexagonal‐boron nitride, graphene, and transition metal dichalcogenides (TMDs). Specifically, …

The wetting behaviour of surfaces is believed to be affected by van der Waals (vdW) forces;
however, there is no clear demonstration of this. With the isolation of two-dimensional vdW …

We report a fully integrated device that can perform both multiple biochemical analysis and
sandwich type immunoassay simultaneously on a disc. The whole blood is applied directly to …

Biomolecular piezoelectric materials are considered a strong candidate material for
biomedical applications due to their robust piezoelectricity, biocompatibility, and low dielectric …